Suico JG - Search Results

1

Serum Lipid and Protein Changes in Healthy Dyslipidemic Subjects Given a Selective Inhibitor of p70 S6 Kinase-1.

Leohr JK, Luffer-Atlas D, Luo MJ, DeBrota DJ, Green C, Mabry TE, Suico JG. Leohr JK, et al. Among authors: suico jg. J Clin Pharmacol. 2018 Apr;58(4):412-424. doi: 10.1002/jcph.1032. Epub 2017 Nov 26. J Clin Pharmacol. 2018. PMID: 29178617 Clinical Trial.

2

Effects of the cholesteryl ester transfer protein inhibitor evacetrapib on lipoproteins, apolipoproteins and 24-h ambulatory blood pressure in healthy adults.

Suico JG, Wang MD, Friedrich S, Cannady EA, Konkoy CS, Ruotolo G, Krueger KA. Suico JG, et al. J Pharm Pharmacol. 2014 Nov;66(11):1576-85. doi: 10.1111/jphp.12287. Epub 2014 Jun 24. J Pharm Pharmacol. 2014. PMID: 24961753 Free PMC article. Clinical Trial.

3

A Multidose Study to Examine the Effect of Food on Evacetrapib Exposure at Steady State.

Small DS, Zhang W, Royalty J, Cannady EA, Downs D, Friedrich S, Suico JG. Small DS, et al. Among authors: suico jg. J Cardiovasc Pharmacol Ther. 2015 Sep;20(5):483-9. doi: 10.1177/1074248415575153. Epub 2015 Mar 3. J Cardiovasc Pharmacol Ther. 2015. PMID: 25736283 Free PMC article. Clinical Trial.

4

CYP-mediated drug-drug interactions with evacetrapib, an investigational CETP inhibitor: in vitro prediction and clinical outcome.

Cannady EA, Suico JG, Wang MD, Friedrich S, Rehmel JR, Nicholls SJ, Krueger KA. Cannady EA, et al. Among authors: suico jg. Br J Clin Pharmacol. 2015 Dec;80(6):1388-98. doi: 10.1111/bcp.12730. Epub 2015 Oct 27. Br J Clin Pharmacol. 2015. PMID: 26264702 Free PMC article. Clinical Trial.

5

Effect of hepatic or renal impairment on the pharmacokinetics of evacetrapib.

Small DS, Zhang W, Royalty J, Cannady EA, Downs D, Ortega D, Suico JG. Small DS, et al. Among authors: suico jg. Eur J Clin Pharmacol. 2016 May;72(5):563-72. doi: 10.1007/s00228-016-2017-1. Epub 2016 Feb 9. Eur J Clin Pharmacol. 2016. PMID: 26857125 Free PMC article. Clinical Trial.

6

Evaluation of the effects of an oral notch inhibitor, crenigacestat (LY3039478), on QT interval, and bioavailability studies conducted in healthy subjects.

Yuen E, Posada M, Smith C, Thorn K, Greenwood D, Burgess M, A Benhadji K, Ortega D, Chinchen L, Suico J. Yuen E, et al. Cancer Chemother Pharmacol. 2019 Mar;83(3):483-492. doi: 10.1007/s00280-018-3750-1. Epub 2018 Dec 11. Cancer Chemother Pharmacol. 2019. PMID: 30539232 Clinical Trial.

7

Evacetrapib at a supratherapeutic steady state concentration does not prolong QT in a thorough QT/QTc study in healthy participants.

Suico JG, Friedrich S, Krueger KA, Zhang W. Suico JG, et al. J Cardiovasc Pharmacol Ther. 2014 May;19(3):283-9. doi: 10.1177/1074248413510784. Epub 2013 Nov 22. J Cardiovasc Pharmacol Ther. 2014. PMID: 24271137 Clinical Trial.

8

Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.

Rorick-Kehn LM, Witcher JW, Lowe SL, Gonzales CR, Weller MA, Bell RL, Hart JC, Need AB, McKinzie JH, Statnick MA, Suico JG, McKinzie DL, Tauscher-Wisniewski S, Mitch CH, Stoltz RR, Wong CJ. Rorick-Kehn LM, et al. Among authors: suico jg. Int J Neuropsychopharmacol. 2014 Oct 31;18(2):pyu036. doi: 10.1093/ijnp/pyu036. Int J Neuropsychopharmacol. 2014. PMID: 25637376 Free PMC article. Clinical Trial.

9

Evacetrapib: in vitro and clinical disposition, metabolism, excretion, and assessment of drug interaction potential with strong CYP3A and CYP2C8 inhibitors.

Cannady EA, Wang MD, Friedrich S, Rehmel JL, Yi P, Small DS, Zhang W, Suico JG. Cannady EA, et al. Among authors: suico jg. Pharmacol Res Perspect. 2015 Oct;3(5):e00179. doi: 10.1002/prp2.179. Epub 2015 Oct 12. Pharmacol Res Perspect. 2015. PMID: 26516590 Free PMC article.

10

Impact of Increased Gastric pH on the Pharmacokinetics of Evacetrapib in Healthy Subjects.

Small DS, Royalty J, Cannady EA, Hale C, Wang MD, Downs D, Suico JG. Small DS, et al. Among authors: suico jg. Pharmacotherapy. 2016 Jul;36(7):749-56. doi: 10.1002/phar.1778. Epub 2016 Jul 8. Pharmacotherapy. 2016. PMID: 27284735 Free PMC article.

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