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Live Attenuated Influenza Vaccines engineered to express the nucleoprotein of a recent isolate stimulate human influenza CD8+ T cells more relevant to current infections.
Korenkov D, Nguyen THO, Isakova-Sivak I, Smolonogina T, Brown LE, Kedzierska K, Rudenko L. Korenkov D, et al. Among authors: kedzierska k. Hum Vaccin Immunother. 2018 Apr 3;14(4):941-946. doi: 10.1080/21645515.2017.1417713. Epub 2018 Jan 23. Hum Vaccin Immunother. 2018. PMID: 29252117 Free PMC article.
Killer T cells in influenza.
Stambas J, Guillonneau C, Kedzierska K, Mintern JD, Doherty PC, La Gruta NL. Stambas J, et al. Among authors: kedzierska k. Pharmacol Ther. 2008 Nov;120(2):186-96. doi: 10.1016/j.pharmthera.2008.08.007. Epub 2008 Aug 28. Pharmacol Ther. 2008. PMID: 18801385 Review.
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW, Rossjohn J, Doherty PC, Turner SJ, Kedzierska K. Valkenburg SA, et al. Among authors: kedzierska k. PLoS Pathog. 2010 Aug 12;6(8):e1001039. doi: 10.1371/journal.ppat.1001039. PLoS Pathog. 2010. PMID: 20711359 Free PMC article.
323 results