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Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner.
Derada Troletti C, Lopes Pinheiro MA, Charabati M, Gowing E, van Het Hof B, van der Pol SMA, Geerts D, Prat A, Fontijn RD, Unger WW, de Vries HE. Derada Troletti C, et al. Among authors: unger ww. Brain Behav Immun. 2018 Mar;69:48-56. doi: 10.1016/j.bbi.2017.12.016. Epub 2017 Dec 28. Brain Behav Immun. 2018. PMID: 29289661
Notch controls generation and function of human effector CD8+ T cells.
Kuijk LM, Verstege MI, Rekers NV, Bruijns SC, Hooijberg E, Roep BO, de Gruijl TD, van Kooyk Y, Unger WW. Kuijk LM, et al. Among authors: unger ww. Blood. 2013 Apr 4;121(14):2638-46. doi: 10.1182/blood-2012-07-442962. Epub 2013 Feb 4. Blood. 2013. PMID: 23380742 Free article.
CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG.
García-Vallejo JJ, Ilarregui JM, Kalay H, Chamorro S, Koning N, Unger WW, Ambrosini M, Montserrat V, Fernandes RJ, Bruijns SC, van Weering JR, Paauw NJ, O'Toole T, van Horssen J, van der Valk P, Nazmi K, Bolscher JG, Bajramovic J, Dijkstra CD, 't Hart BA, van Kooyk Y. García-Vallejo JJ, et al. Among authors: unger ww. J Exp Med. 2014 Jun 30;211(7):1465-83. doi: 10.1084/jem.20122192. Epub 2014 Jun 16. J Exp Med. 2014. PMID: 24935259 Free PMC article. Clinical Trial.
Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells.
Fehres CM, Duinkerken S, Bruijns SC, Kalay H, van Vliet SJ, Ambrosini M, de Gruijl TD, Unger WW, Garcia-Vallejo JJ, van Kooyk Y. Fehres CM, et al. Among authors: unger ww. Cell Mol Immunol. 2017 Apr;14(4):360-370. doi: 10.1038/cmi.2015.87. Epub 2015 Oct 12. Cell Mol Immunol. 2017. PMID: 26456691 Free PMC article.
Mycoplasma pneumoniae Compared to Streptococcus pneumoniae Avoids Induction of Proinflammatory Epithelial Cell Responses despite Robustly Inducing TLR2 Signaling.
de Groot RCA, Zhu H, Hoogenboezem T, de Bruijn ACJM, Eenjes E, 't Jong AEJ, Belo AI, Estevão SC, Bajramovic JJ, Rottier RJ, Kool M, van Rossum AMC, Unger WWJ. de Groot RCA, et al. Among authors: unger wwj. Infect Immun. 2022 Aug 18;90(8):e0012922. doi: 10.1128/iai.00129-22. Epub 2022 Jul 11. Infect Immun. 2022. PMID: 35862703 Free PMC article.
71 results