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Page 1
Functional interrogation and mining of natively paired human VH:VL antibody repertoires.
Wang B, DeKosky BJ, Timm MR, Lee J, Normandin E, Misasi J, Kong R, McDaniel JR, Delidakis G, Leigh KE, Niezold T, Choi CW, Viox EG, Fahad A, Cagigi A, Ploquin A, Leung K, Yang ES, Kong WP, Voss WN, Schmidt AG, Moody MA, Ambrozak DR, Henry AR, Laboune F, Ledgerwood JE, Graham BS, Connors M, Douek DC, Sullivan NJ, Ellington AD, Mascola JR, Georgiou G. Wang B, et al. Among authors: delidakis g. Nat Biotechnol. 2018 Feb;36(2):152-155. doi: 10.1038/nbt.4052. Epub 2018 Jan 8. Nat Biotechnol. 2018. PMID: 29309060 Free PMC article.
A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires.
Tanno H, McDaniel JR, Stevens CA, Voss WN, Li J, Durrett R, Lee J, Gollihar J, Tanno Y, Delidakis G, Pothukuchy A, Ellefson JW, Goronzy JJ, Maynard JA, Ellington AD, Ippolito GC, Georgiou G. Tanno H, et al. Among authors: delidakis g. Sci Adv. 2020 Apr 22;6(17):eaay9093. doi: 10.1126/sciadv.aay9093. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32426460 Free PMC article.
An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
Lee CH, Kang TH, Godon O, Watanabe M, Delidakis G, Gillis CM, Sterlin D, Hardy D, Cogné M, Macdonald LE, Murphy AJ, Tu N, Lee J, McDaniel JR, Makowski E, Tessier PM, Meyer AS, Bruhns P, Georgiou G. Lee CH, et al. Among authors: delidakis g. Nat Commun. 2019 Nov 6;10(1):5031. doi: 10.1038/s41467-019-13108-2. Nat Commun. 2019. PMID: 31695028 Free PMC article.
An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages.
Kang TH, Lee CH, Delidakis G, Jung J, Richard-Le Goff O, Lee J, Kim JE, Charab W, Bruhns P, Georgiou G. Kang TH, et al. Among authors: delidakis g. Front Immunol. 2019 Mar 27;10:562. doi: 10.3389/fimmu.2019.00562. eCollection 2019. Front Immunol. 2019. PMID: 30984171 Free PMC article.
Publisher Correction: An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
Lee CH, Kang TH, Godon O, Watanabe M, Delidakis G, Gillis CM, Sterlin D, Hardy D, Cogné M, Macdonald LE, Murphy AJ, Tu N, Lee J, McDaniel JR, Makowski E, Tessier PM, Meyer AS, Bruhns P, Georgiou G. Lee CH, et al. Among authors: delidakis g. Nat Commun. 2019 Nov 26;10(1):5461. doi: 10.1038/s41467-019-13458-x. Nat Commun. 2019. PMID: 31767870 Free PMC article.
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Voss WN, Hou YJ, Johnson NV, Delidakis G, Kim JE, Javanmardi K, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Chou CW, Abbasi SA, Pickens W, George K, Boutz DR, Towers DM, McDaniel JR, Billick D, Goike J, Rowe L, Batra D, Pohl J, Lee J, Gangappa S, Sambhara S, Gadush M, Wang N, Person MD, Iverson BL, Gollihar JD, Dye JM, Herbert AS, Finkelstein IJ, Baric RS, McLellan JS, Georgiou G, Lavinder JJ, Ippolito GC. Voss WN, et al. Among authors: delidakis g. Science. 2021 Jun 4;372(6546):1108-1112. doi: 10.1126/science.abg5268. Epub 2021 May 4. Science. 2021. PMID: 33947773 Free PMC article.
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.
Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G. Lee CH, et al. Among authors: delidakis g. Nat Immunol. 2017 Aug;18(8):889-898. doi: 10.1038/ni.3770. Epub 2017 Jun 12. Nat Immunol. 2017. PMID: 28604720 Free PMC article.
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma.
Voss WN, Hou YJ, Johnson NV, Kim JE, Delidakis G, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Abbasi SA, Pickens W, George K, Boutz DR, Towers DM, McDaniel JR, Billick D, Goike J, Rowe L, Batra D, Pohl J, Lee J, Gangappa S, Sambhara S, Gadush M, Wang N, Person MD, Iverson BL, Gollihar JD, Dye J, Herbert A, Baric RS, McLellan JS, Georgiou G, Lavinder JJ, Ippolito GC. Voss WN, et al. Among authors: delidakis g. bioRxiv [Preprint]. 2020 Dec 21:2020.12.20.423708. doi: 10.1101/2020.12.20.423708. bioRxiv. 2020. PMID: 33398269 Free PMC article. Updated. Preprint.
Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.
Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G. Lee CH, et al. Among authors: delidakis g. Nat Immunol. 2017 Sep 19;18(10):1173. doi: 10.1038/ni1017-1173c. Nat Immunol. 2017. PMID: 28926542 No abstract available.
12 results