Ellington AD - Search Results

1

Functional interrogation and mining of natively paired human V_H:V_L antibody repertoires.

Wang B, DeKosky BJ, Timm MR, Lee J, Normandin E, Misasi J, Kong R, McDaniel JR, Delidakis G, Leigh KE, Niezold T, Choi CW, Viox EG, Fahad A, Cagigi A, Ploquin A, Leung K, Yang ES, Kong WP, Voss WN, Schmidt AG, Moody MA, Ambrozak DR, Henry AR, Laboune F, Ledgerwood JE, Graham BS, Connors M, Douek DC, Sullivan NJ, Ellington AD, Mascola JR, Georgiou G. Wang B, et al. Among authors: ellington ad. Nat Biotechnol. 2018 Feb;36(2):152-155. doi: 10.1038/nbt.4052. Epub 2018 Jan 8. Nat Biotechnol. 2018. PMID: 29309060 Free PMC article.

2

Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer.

Cox JC, Hayhurst A, Hesselberth J, Bayer TS, Georgiou G, Ellington AD. Cox JC, et al. Among authors: ellington ad. Nucleic Acids Res. 2002 Oct 15;30(20):e108. doi: 10.1093/nar/gnf107. Nucleic Acids Res. 2002. PMID: 12384610 Free PMC article.

3

Engineering antibody fragments to fold in the absence of disulfide bonds.

Seo MJ, Jeong KJ, Leysath CE, Ellington AD, Iverson BL, Georgiou G. Seo MJ, et al. Among authors: ellington ad. Protein Sci. 2009 Feb;18(2):259-67. doi: 10.1002/pro.31. Protein Sci. 2009. PMID: 19177559 Free PMC article.

4

Rapid construction and characterization of synthetic antibody libraries without DNA amplification.

Ge X, Mazor Y, Hunicke-Smith SP, Ellington AD, Georgiou G. Ge X, et al. Among authors: ellington ad. Biotechnol Bioeng. 2010 Jun 15;106(3):347-57. doi: 10.1002/bit.22712. Biotechnol Bioeng. 2010. PMID: 20198660

5

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells.

Reddy ST, Ge X, Miklos AE, Hughes RA, Kang SH, Hoi KH, Chrysostomou C, Hunicke-Smith SP, Iverson BL, Tucker PW, Ellington AD, Georgiou G. Reddy ST, et al. Among authors: ellington ad. Nat Biotechnol. 2010 Sep;28(9):965-9. doi: 10.1038/nbt.1673. Epub 2010 Aug 29. Nat Biotechnol. 2010. PMID: 20802495

6

Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.

Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T, Zemlin M, Shultz LD, Ellington AD, Vandenberg CL, Georgiou G. Ippolito GC, et al. Among authors: ellington ad. PLoS One. 2012;7(4):e35497. doi: 10.1371/journal.pone.0035497. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558161 Free PMC article.

7

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.

DeKosky BJ, Ippolito GC, Deschner RP, Lavinder JJ, Wine Y, Rawlings BM, Varadarajan N, Giesecke C, Dörner T, Andrews SF, Wilson PC, Hunicke-Smith SP, Willson CG, Ellington AD, Georgiou G. DeKosky BJ, et al. Among authors: ellington ad. Nat Biotechnol. 2013 Feb;31(2):166-9. doi: 10.1038/nbt.2492. Epub 2013 Jan 20. Nat Biotechnol. 2013. PMID: 23334449 Free PMC article.

8

Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response.

Wine Y, Boutz DR, Lavinder JJ, Miklos AE, Hughes RA, Hoi KH, Jung ST, Horton AP, Murrin EM, Ellington AD, Marcotte EM, Georgiou G. Wine Y, et al. Among authors: ellington ad. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2993-8. doi: 10.1073/pnas.1213737110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382245 Free PMC article.

9

Endowing cells with logic and memory.

Maranhao AC, Ellington AD. Maranhao AC, et al. Among authors: ellington ad. Nat Biotechnol. 2013 May;31(5):413-5. doi: 10.1038/nbt.2573. Nat Biotechnol. 2013. PMID: 23657394 No abstract available.

10

Directed evolution of genetic parts and circuits by compartmentalized partnered replication.

Ellefson JW, Meyer AJ, Hughes RA, Cannon JR, Brodbelt JS, Ellington AD. Ellefson JW, et al. Among authors: ellington ad. Nat Biotechnol. 2014 Jan;32(1):97-101. doi: 10.1038/nbt.2714. Epub 2013 Nov 3. Nat Biotechnol. 2014. PMID: 24185096

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