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Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study.
Beigel JH, Voell J, Kumar P, Raviprakash K, Wu H, Jiao JA, Sullivan E, Luke T, Davey RT Jr. Beigel JH, et al. Among authors: luke t. Lancet Infect Dis. 2018 Apr;18(4):410-418. doi: 10.1016/S1473-3099(18)30002-1. Epub 2018 Jan 9. Lancet Infect Dis. 2018. PMID: 29329957 Free PMC article. Clinical Trial.
Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo.
Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, Wang J, Nie W, Smith G, Hensley LE, Olinger GG, Kuhn JH, Holbrook MR, Johnson RF, Perlman S, Sullivan E, Frieman MB. Luke T, et al. Sci Transl Med. 2016 Feb 17;8(326):326ra21. doi: 10.1126/scitranslmed.aaf1061. Sci Transl Med. 2016. PMID: 26888429
Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study.
Beigel JH, Tebas P, Elie-Turenne MC, Bajwa E, Bell TE, Cairns CB, Shoham S, Deville JG, Feucht E, Feinberg J, Luke T, Raviprakash K, Danko J, O'Neil D, Metcalf JA, King K, Burgess TH, Aga E, Lane HC, Hughes MD, Davey RT; IRC002 Study Team. Beigel JH, et al. Among authors: luke t. Lancet Respir Med. 2017 Jun;5(6):500-511. doi: 10.1016/S2213-2600(17)30174-1. Epub 2017 May 15. Lancet Respir Med. 2017. PMID: 28522352 Free PMC article. Clinical Trial.
Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate.
Luke T, Bennett RS, Gerhardt DM, Burdette T, Postnikova E, Mazur S, Honko AN, Oberlander N, Byrum R, Ragland D, St Claire M, Janosko KB, Smith G, Glenn G, Hooper J, Dye J, Pal S, Bishop-Lilly KA, Hamilton T, Frey K, Bollinger L, Wada J, Wu H, Jiao JA, Olinger GG, Gunn B, Alter G, Khurana S, Hensley LE, Sullivan E, Jahrling PB. Luke T, et al. J Infect Dis. 2018 Nov 22;218(suppl_5):S636-S648. doi: 10.1093/infdis/jiy377. J Infect Dis. 2018. PMID: 30010950 Free PMC article.
Influence of sample collection tube method, anticoagulant-containing plasma versus serum, on influenza virus hemagglutination inhibition titer and microneutralization titer serological assays.
Morrison BJ, Martin NJ, Rehman T, Ewing D, Dewar RL, Metcalf J, Sun P, Beigel J, Luke TC, Raviprakash K. Morrison BJ, et al. Among authors: luke tc. BMC Health Serv Res. 2018 Aug 22;18(1):651. doi: 10.1186/s12913-018-3465-3. BMC Health Serv Res. 2018. PMID: 30134892 Free PMC article.
93 results