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MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape.
Menachery VD, Schäfer A, Burnum-Johnson KE, Mitchell HD, Eisfeld AJ, Walters KB, Nicora CD, Purvine SO, Casey CP, Monroe ME, Weitz KK, Stratton KG, Webb-Robertson BM, Gralinski LE, Metz TO, Smith RD, Waters KM, Sims AC, Kawaoka Y, Baric RS. Menachery VD, et al. Among authors: eisfeld aj. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E1012-E1021. doi: 10.1073/pnas.1706928115. Epub 2018 Jan 16. Proc Natl Acad Sci U S A. 2018. PMID: 29339515 Free PMC article.
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque.
Shinya K, Gao Y, Cilloniz C, Suzuki Y, Fujie M, Deng G, Zhu Q, Fan S, Makino A, Muramoto Y, Fukuyama S, Tamura D, Noda T, Eisfeld AJ, Katze MG, Chen H, Kawaoka Y. Shinya K, et al. Among authors: eisfeld aj. J Virol. 2012 Jun;86(11):6055-66. doi: 10.1128/JVI.00365-12. Epub 2012 Apr 4. J Virol. 2012. PMID: 22491448 Free PMC article.
Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice.
Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, Baric R, Kawaoka Y, Katze MG. Tchitchek N, et al. Among authors: eisfeld aj. BMC Syst Biol. 2013 Jul 29;7:69. doi: 10.1186/1752-0509-7-69. BMC Syst Biol. 2013. PMID: 23895213 Free PMC article.
42 results