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Regulation of amyloid-β dynamics and pathology by the circadian clock.
Kress GJ, Liao F, Dimitry J, Cedeno MR, FitzGerald GA, Holtzman DM, Musiek ES. Kress GJ, et al. Among authors: holtzman dm. J Exp Med. 2018 Apr 2;215(4):1059-1068. doi: 10.1084/jem.20172347. Epub 2018 Jan 30. J Exp Med. 2018. PMID: 29382695 Free PMC article.
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
Fryer JD, Demattos RB, McCormick LM, O'Dell MA, Spinner ML, Bales KR, Paul SM, Sullivan PM, Parsadanian M, Bu G, Holtzman DM. Fryer JD, et al. Among authors: holtzman dm. J Biol Chem. 2005 Jul 8;280(27):25754-9. doi: 10.1074/jbc.M502143200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15888448 Free article.
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.
Cirrito JR, Yamada KA, Finn MB, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, Holtzman DM. Cirrito JR, et al. Among authors: holtzman dm. Neuron. 2005 Dec 22;48(6):913-22. doi: 10.1016/j.neuron.2005.10.028. Neuron. 2005. PMID: 16364896 Free article.
Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle.
Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Kang JE, et al. Among authors: holtzman dm. Science. 2009 Nov 13;326(5955):1005-7. doi: 10.1126/science.1180962. Epub 2009 Sep 24. Science. 2009. PMID: 19779148 Free PMC article.
694 results