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The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis.
Hepatol Commun. 2017 Jun 19;1(6):524-537. doi: 10.1002/hep4.1057. eCollection 2017 Aug.
Hepatol Commun. 2017.
PMID: 29404476
Free PMC article.
Brown adipose tissue: a potential target in the fight against obesity and the metabolic syndrome.
Poekes L, Lanthier N, Leclercq IA.
Poekes L, et al.
Clin Sci (Lond). 2015 Dec;129(11):933-49. doi: 10.1042/CS20150339.
Clin Sci (Lond). 2015.
PMID: 26359253
Review.
Item in Clipboard
Activation of brown adipose tissue enhances the efficacy of caloric restriction for treatment of nonalcoholic steatohepatitis.
Poekes L, Gillard J, Farrell GC, Horsmans Y, Leclercq IA.
Poekes L, et al.
Lab Invest. 2019 Jan;99(1):4-16. doi: 10.1038/s41374-018-0120-x. Epub 2018 Sep 26.
Lab Invest. 2019.
PMID: 30258096
Free article.
Item in Clipboard
Defective adaptive thermogenesis contributes to metabolic syndrome and liver steatosis in obese mice.
Poekes L, Legry V, Schakman O, Detrembleur C, Bol A, Horsmans Y, Farrell GC, Leclercq IA.
Poekes L, et al.
Clin Sci (Lond). 2017 Feb 1;131(4):285-296. doi: 10.1042/CS20160469. Epub 2016 Nov 1.
Clin Sci (Lond). 2017.
PMID: 27803297
Item in Clipboard
Obeticholic acid improves adipose morphometry and inflammation and reduces steatosis in dietary but not metabolic obesity in mice.
Haczeyni F, Poekes L, Wang H, Mridha AR, Barn V, Geoffrey Haigh W, Ioannou GN, Yeh MM, Leclercq IA, Teoh NC, Farrell GC.
Haczeyni F, et al. Among authors: poekes l.
Obesity (Silver Spring). 2017 Jan;25(1):155-165. doi: 10.1002/oby.21701. Epub 2016 Nov 2.
Obesity (Silver Spring). 2017.
PMID: 27804232
Free PMC article.
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Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fed foz/foz mice.
Legry V, Van Rooyen DM, Lambert B, Sempoux C, Poekes L, Español-Suñer R, Molendi-Coste O, Horsmans Y, Farrell GC, Leclercq IA.
Legry V, et al. Among authors: poekes l.
Clin Sci (Lond). 2014 Oct;127(7):507-18. doi: 10.1042/CS20140026.
Clin Sci (Lond). 2014.
PMID: 24766485
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