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Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase.
J Invest Dermatol. 2018 Jul;138(7):1601-1608. doi: 10.1016/j.jid.2018.01.019. Epub 2018 Feb 7.
J Invest Dermatol. 2018.
PMID: 29427586
Free article.
Clinical Trial.
4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation.
Kolbe L, Mann T, Gerwat W, Batzer J, Ahlheit S, Scherner C, Wenck H, Stäb F.
Kolbe L, et al. Among authors: gerwat w.
J Eur Acad Dermatol Venereol. 2013 Jan;27 Suppl 1:19-23. doi: 10.1111/jdv.12051.
J Eur Acad Dermatol Venereol. 2013.
PMID: 23205541
Clinical Trial.
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Human tyrosinase is able to oxidize both enantiomers of rhododendrol.
Ito S, Gerwat W, Kolbe L, Yamashita T, Ojika M, Wakamatsu K.
Ito S, et al. Among authors: gerwat w.
Pigment Cell Melanoma Res. 2014 Nov;27(6):1149-53. doi: 10.1111/pcmr.12300. Epub 2014 Sep 3.
Pigment Cell Melanoma Res. 2014.
PMID: 25130058
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The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin.
Choi W, Wolber R, Gerwat W, Mann T, Batzer J, Smuda C, Liu H, Kolbe L, Hearing VJ.
Choi W, et al. Among authors: gerwat w.
J Cell Sci. 2010 Sep 15;123(Pt 18):3102-11. doi: 10.1242/jcs.064774. Epub 2010 Aug 24.
J Cell Sci. 2010.
PMID: 20736300
Free PMC article.
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Photoaging of human retinal pigment epithelium is accompanied by oxidative modifications of its eumelanin.
Ito S, Pilat A, Gerwat W, Skumatz CM, Ito M, Kiyono A, Zadlo A, Nakanishi Y, Kolbe L, Burke JM, Sarna T, Wakamatsu K.
Ito S, et al. Among authors: gerwat w.
Pigment Cell Melanoma Res. 2013 May;26(3):357-66. doi: 10.1111/pcmr.12078. Epub 2013 Mar 27.
Pigment Cell Melanoma Res. 2013.
PMID: 23421783
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Multidirectional activity of bakuchiol against cellular mechanisms of facial ageing - Experimental evidence for a holistic treatment approach.
Bluemke A, Ring AP, Immeyer J, Hoff A, Eisenberg T, Gerwat W, Meyer F, Breitkreutz S, Klinger LM, Brandner JM, Sandig G, Seifert M, Segger D, Rippke F, Schweiger D.
Bluemke A, et al. Among authors: gerwat w.
Int J Cosmet Sci. 2022 Jun;44(3):377-393. doi: 10.1111/ics.12784. Epub 2022 Jun 9.
Int J Cosmet Sci. 2022.
PMID: 35514037
Free PMC article.
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