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The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.
J Immunol. 2018 Apr 15;200(8):2860-2868. doi: 10.4049/jimmunol.1700228. Epub 2018 Mar 5.
J Immunol. 2018.
PMID: 29507106
Free article.
The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer.
Hafstrand I, Doorduijn EM, Duru AD, Buratto J, Oliveira CC, Sandalova T, van Hall T, Achour A.
Hafstrand I, et al.
J Immunol. 2016 Mar 1;196(5):2327-34. doi: 10.4049/jimmunol.1502249. Epub 2016 Jan 22.
J Immunol. 2016.
PMID: 26800871
Free article.
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Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
Hafstrand I, Badia-Martinez D, Josey BJ, Norström M, Buratto J, Pellegrino S, Duru AD, Sandalova T, Achour A.
Hafstrand I, et al.
PLoS One. 2017 Dec 18;12(12):e0189584. doi: 10.1371/journal.pone.0189584. eCollection 2017.
PLoS One. 2017.
PMID: 29253009
Free PMC article.
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Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Hafstrand I, Sayitoglu EC, Apavaloaei A, Josey BJ, Sun R, Han X, Pellegrino S, Ozkazanc D, Potens R, Janssen L, Nilvebrant J, Nygren PÅ, Sandalova T, Springer S, Georgoudaki AM, Duru AD, Achour A.
Hafstrand I, et al.
Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5055-5060. doi: 10.1073/pnas.1807656116. Epub 2019 Feb 26.
Proc Natl Acad Sci U S A. 2019.
PMID: 30808808
Free PMC article.
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Why TAPBPR? Implications of an additional player in MHC class I peptide presentation.
Hafstrand I, Aflalo A, Boyle LH.
Hafstrand I, et al.
Curr Opin Immunol. 2021 Jun;70:90-94. doi: 10.1016/j.coi.2021.04.011. Epub 2021 May 27.
Curr Opin Immunol. 2021.
PMID: 34052734
Review.
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