Campbell AE - Search Results

1

NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins.

Campbell AE, Shadle SC, Jagannathan S, Lim JW, Resnick R, Tawil R, van der Maarel SM, Tapscott SJ. Campbell AE, et al. Elife. 2018 Mar 13;7:e31023. doi: 10.7554/eLife.31023. Elife. 2018. PMID: 29533181 Free PMC article.

2

DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy.

Shadle SC, Zhong JW, Campbell AE, Conerly ML, Jagannathan S, Wong CJ, Morello TD, van der Maarel SM, Tapscott SJ. Shadle SC, et al. Among authors: campbell ae. PLoS Genet. 2017 Mar 8;13(3):e1006658. doi: 10.1371/journal.pgen.1006658. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28273136 Free PMC article.

3

BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells.

Campbell AE, Oliva J, Yates MP, Zhong JW, Shadle SC, Snider L, Singh N, Tai S, Hiramuki Y, Tawil R, van der Maarel SM, Tapscott SJ, Sverdrup FM. Campbell AE, et al. Skelet Muscle. 2017 Sep 4;7(1):16. doi: 10.1186/s13395-017-0134-x. Skelet Muscle. 2017. PMID: 28870238 Free PMC article.

4

Facioscapulohumeral dystrophy: activating an early embryonic transcriptional program in human skeletal muscle.

Campbell AE, Belleville AE, Resnick R, Shadle SC, Tapscott SJ. Campbell AE, et al. Hum Mol Genet. 2018 Aug 1;27(R2):R153-R162. doi: 10.1093/hmg/ddy162. Hum Mol Genet. 2018. PMID: 29718206 Free PMC article. Review.

5

MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD.

Wang LH, Friedman SD, Shaw D, Snider L, Wong CJ, Budech CB, Poliachik SL, Gove NE, Lewis LM, Campbell AE, Lemmers RJFL, Maarel SM, Tapscott SJ, Tawil RN. Wang LH, et al. Among authors: campbell ae. Hum Mol Genet. 2019 Feb 1;28(3):476-486. doi: 10.1093/hmg/ddy364. Hum Mol Genet. 2019. PMID: 30312408 Free PMC article.

6

Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy.

Oliva J, Galasinski S, Richey A, Campbell AE, Meyers MJ, Modi N, Zhong JW, Tawil R, Tapscott SJ, Sverdrup FM. Oliva J, et al. Among authors: campbell ae. J Pharmacol Exp Ther. 2019 Aug;370(2):219-230. doi: 10.1124/jpet.119.259663. Epub 2019 Jun 12. J Pharmacol Exp Ther. 2019. PMID: 31189728 Free PMC article.

7

DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade.

Chew GL, Campbell AE, De Neef E, Sutliff NA, Shadle SC, Tapscott SJ, Bradley RK. Chew GL, et al. Among authors: campbell ae. Dev Cell. 2019 Sep 9;50(5):658-671.e7. doi: 10.1016/j.devcel.2019.06.011. Epub 2019 Jul 18. Dev Cell. 2019. PMID: 31327741 Free PMC article.

8

DUX4-induced bidirectional HSATII satellite repeat transcripts form intranuclear double-stranded RNA foci in human cell models of FSHD.

Shadle SC, Bennett SR, Wong CJ, Karreman NA, Campbell AE, van der Maarel SM, Bass BL, Tapscott SJ. Shadle SC, et al. Among authors: campbell ae. Hum Mol Genet. 2019 Dec 1;28(23):3997-4011. doi: 10.1093/hmg/ddz242. Hum Mol Genet. 2019. PMID: 31630170 Free PMC article.

9

Longitudinal measures of RNA expression and disease activity in FSHD muscle biopsies.

Wong CJ, Wang LH, Friedman SD, Shaw D, Campbell AE, Budech CB, Lewis LM, Lemmers RJFL, Statland JM, van der Maarel SM, Tawil RN, Tapscott SJ. Wong CJ, et al. Among authors: campbell ae. Hum Mol Genet. 2020 Apr 15;29(6):1030-1043. doi: 10.1093/hmg/ddaa031. Hum Mol Genet. 2020. PMID: 32083293 Free PMC article.

10

Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction.

Spens AE, Sutliff NA, Bennett SR, Campbell AE, Tapscott SJ. Spens AE, et al. Among authors: campbell ae. Elife. 2023 Apr 24;12:e82057. doi: 10.7554/eLife.82057. Elife. 2023. PMID: 37092726 Free PMC article.

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