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Isavuconazole treatment for rare fungal diseases and for invasive aspergillosis in patients with renal impairment: Challenges and lessons of the VITAL trial.
Perfect JR, Cornely OA, Heep M, Ostrosky-Zeichner L, Mullane KM, Maher R, Croos-Dabrera R, Lademacher C, Engelhardt M, Chen C, Marty FM. Perfect JR, et al. Among authors: heep m. Mycoses. 2018 Jul;61(7):420-429. doi: 10.1111/myc.12769. Epub 2018 Apr 19. Mycoses. 2018. PMID: 29570857 Free PMC article. Review.
Effect of mild and moderate liver disease on the pharmacokinetics of isavuconazole after intravenous and oral administration of a single dose of the prodrug BAL8557.
Schmitt-Hoffmann A, Roos B, Spickermann J, Heep M, Peterfaí E, Edwards DJ, Stoeckel K. Schmitt-Hoffmann A, et al. Among authors: heep m. Antimicrob Agents Chemother. 2009 Nov;53(11):4885-90. doi: 10.1128/AAC.00319-09. Epub 2009 Aug 10. Antimicrob Agents Chemother. 2009. PMID: 19667286 Free PMC article. Clinical Trial.
Multiple-dose pharmacokinetics and safety of the new antifungal triazole BAL4815 after intravenous infusion and oral administration of its prodrug, BAL8557, in healthy volunteers.
Schmitt-Hoffmann A, Roos B, Maares J, Heep M, Spickerman J, Weidekamm E, Brown T, Roehrle M. Schmitt-Hoffmann A, et al. Among authors: heep m. Antimicrob Agents Chemother. 2006 Jan;50(1):286-93. doi: 10.1128/AAC.50.1.286-293.2006. Antimicrob Agents Chemother. 2006. PMID: 16377699 Free PMC article. Clinical Trial.
Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL4815 after intravenous infusions (50, 100, and 200 milligrams) and oral administrations (100, 200, and 400 milligrams) of its prodrug, BAL8557, in healthy volunteers.
Schmitt-Hoffmann A, Roos B, Heep M, Schleimer M, Weidekamm E, Brown T, Roehrle M, Beglinger C. Schmitt-Hoffmann A, et al. Among authors: heep m. Antimicrob Agents Chemother. 2006 Jan;50(1):279-85. doi: 10.1128/AAC.50.1.279-285.2006. Antimicrob Agents Chemother. 2006. PMID: 16377698 Free PMC article. Clinical Trial.
44 results