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77 results

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Page 1
Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).
Welte T, Dellinger RP, Ebelt H, Ferrer M, Opal SM, Singer M, Vincent JL, Werdan K, Martin-Loeches I, Almirall J, Artigas A, Ignacio Ayestarán J, Nuding S, Ferrer R, Sirgo Rodríguez G, Shankar-Hari M, Álvarez-Lerma F, Riessen R, Sirvent JM, Kluge S, Zacharowski K, Bonastre Mora J, Lapp H, Wöbker G, Achtzehn U, Brealey D, Kempa A, Sánchez García M, Brederlau J, Kochanek M, Reschreiter HP, Wise MP, Belohradsky BH, Bobenhausen I, Dälken B, Dubovy P, Langohr P, Mayer M, Schüttrumpf J, Wartenberg-Demand A, Wippermann U, Wolf D, Torres A. Welte T, et al. Among authors: brederlau j. Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9. Intensive Care Med. 2018. PMID: 29632995 Free PMC article. Clinical Trial.
Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study.
Bein T, Weber-Carstens S, Goldmann A, Müller T, Staudinger T, Brederlau J, Muellenbach R, Dembinski R, Graf BM, Wewalka M, Philipp A, Wernecke KD, Lubnow M, Slutsky AS. Bein T, et al. Among authors: brederlau j. Intensive Care Med. 2013 May;39(5):847-56. doi: 10.1007/s00134-012-2787-6. Epub 2013 Jan 10. Intensive Care Med. 2013. PMID: 23306584 Free PMC article. Clinical Trial.
Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial.
Rüddel H, Thomas-Rüddel DO, Reinhart K, Bach F, Gerlach H, Lindner M, Marshall JC, Simon P, Weiss M, Bloos F, Schwarzkopf D; MEDUSA study group. Rüddel H, et al. Crit Care. 2022 Feb 28;26(1):51. doi: 10.1186/s13054-022-03901-9. Crit Care. 2022. PMID: 35227308 Free PMC article. Clinical Trial.
A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis.
Schwarzkopf D, Matthaeus-Kraemer CT, Thomas-Rüddel DO, Rüddel H, Poidinger B, Bach F, Gerlach H, Gründling M, Lindner M, Scheer C, Simon P, Weiss M, Reinhart K, Bloos F; MEDUSA study group. Schwarzkopf D, et al. Sci Rep. 2022 Mar 10;12(1):3925. doi: 10.1038/s41598-022-07915-9. Sci Rep. 2022. PMID: 35273276 Free PMC article.
Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature.
Thomas-Rüddel DO, Hoffmann P, Schwarzkopf D, Scheer C, Bach F, Komann M, Gerlach H, Weiss M, Lindner M, Rüddel H, Simon P, Kuhn SO, Wetzker R, Bauer M, Reinhart K, Bloos F; MEDUSA study group. Thomas-Rüddel DO, et al. Crit Care. 2021 Oct 21;25(1):368. doi: 10.1186/s13054-021-03776-2. Crit Care. 2021. PMID: 34674733 Free PMC article. Clinical Trial.
The effect of a novel extracorporeal cytokine hemoadsorption device on IL-6 elimination in septic patients: A randomized controlled trial.
Schädler D, Pausch C, Heise D, Meier-Hellmann A, Brederlau J, Weiler N, Marx G, Putensen C, Spies C, Jörres A, Quintel M, Engel C, Kellum JA, Kuhlmann MK. Schädler D, et al. Among authors: brederlau j. PLoS One. 2017 Oct 30;12(10):e0187015. doi: 10.1371/journal.pone.0187015. eCollection 2017. PLoS One. 2017. PMID: 29084247 Free PMC article. Clinical Trial.
[If the extracorporeal lung assist comes to its limit: use and management of extracorporeal membrane oxygenation in severe acute respiratory distress syndrome].
Küstermann J, Brederlau J, Kranke P, Roewer N, Muellenbach RM. Küstermann J, et al. Among authors: brederlau j. Anasthesiol Intensivmed Notfallmed Schmerzther. 2012 Oct;47(10):646-54. doi: 10.1055/s-0032-1329402. Epub 2012 Oct 24. Anasthesiol Intensivmed Notfallmed Schmerzther. 2012. PMID: 23097209 Review. German.
77 results