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315 results

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Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).
Welte T, Dellinger RP, Ebelt H, Ferrer M, Opal SM, Singer M, Vincent JL, Werdan K, Martin-Loeches I, Almirall J, Artigas A, Ignacio Ayestarán J, Nuding S, Ferrer R, Sirgo Rodríguez G, Shankar-Hari M, Álvarez-Lerma F, Riessen R, Sirvent JM, Kluge S, Zacharowski K, Bonastre Mora J, Lapp H, Wöbker G, Achtzehn U, Brealey D, Kempa A, Sánchez García M, Brederlau J, Kochanek M, Reschreiter HP, Wise MP, Belohradsky BH, Bobenhausen I, Dälken B, Dubovy P, Langohr P, Mayer M, Schüttrumpf J, Wartenberg-Demand A, Wippermann U, Wolf D, Torres A. Welte T, et al. Among authors: opal sm. Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9. Intensive Care Med. 2018. PMID: 29632995 Free PMC article. Clinical Trial.
Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation - The CIGMA study.
Welte T, Dellinger RP, Ebelt H, Ferrer M, Opal SM, Schliephake DE, Wartenberg-Demand A, Werdan K, Löffler K, Torres A. Welte T, et al. Among authors: opal sm. Respir Med. 2015 Jun;109(6):758-67. doi: 10.1016/j.rmed.2015.03.008. Epub 2015 Apr 2. Respir Med. 2015. PMID: 25887136 Free article. Clinical Trial.
The authors reply.
Opal SM, Dellinger RP. Opal SM, et al. Crit Care Med. 2013 Dec;41(12):e488. doi: 10.1097/CCM.0000000000000059. Crit Care Med. 2013. PMID: 24275421 No abstract available.
The authors reply.
Opal SM, Dellinger RP, Vincent JL, Masur H, Angus DC. Opal SM, et al. Crit Care Med. 2014 Dec;42(12):e798-9. doi: 10.1097/CCM.0000000000000681. Crit Care Med. 2014. PMID: 25402303 No abstract available.
Sepsis: frontiers in supportive care, organisation and research.
Perner A, Rhodes A, Venkatesh B, Angus DC, Martin-Loeches I, Preiser JC, Vincent JL, Marshall J, Reinhart K, Joannidis M, Opal SM. Perner A, et al. Among authors: opal sm. Intensive Care Med. 2017 Apr;43(4):496-508. doi: 10.1007/s00134-017-4677-4. Epub 2017 Jan 27. Intensive Care Med. 2017. PMID: 28130686 Review.
Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial.
Dellinger RP, Tomayko JF, Angus DC, Opal S, Cupo MA, McDermott S, Ducher A, Calandra T, Cohen J; Lipid Infusion and Patient Outcomes in Sepsis (LIPOS) Investigators. Dellinger RP, et al. Crit Care Med. 2009 Nov;37(11):2929-38. doi: 10.1097/CCM.0b013e3181b0266c. Crit Care Med. 2009. PMID: 19770753 Clinical Trial.
Coagulation in sepsis.
Amaral A, Opal SM, Vincent JL. Amaral A, et al. Among authors: opal sm. Intensive Care Med. 2004 Jun;30(6):1032-40. doi: 10.1007/s00134-004-2291-8. Epub 2004 May 18. Intensive Care Med. 2004. PMID: 15148567 Review.
315 results