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Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, Duncan D, Bregman H, Keskin A, Santeford A, Apte RS, Sehgal R, Johnson B, Amarasinghe GK, Soares MP, Satoh T, Akira S, Hai T, de Guzman Strong C, Auclair K, Roddy TP, Biller SA, Jovanovic M, Klechevsky E, Stewart KM, Randolph GJ, Artyomov MN. Bambouskova M, et al. Among authors: randolph gj. Nature. 2018 Apr;556(7702):501-504. doi: 10.1038/s41586-018-0052-z. Epub 2018 Apr 18. Nature. 2018. PMID: 29670287 Free PMC article.
Deciphering the transcriptional network of the dendritic cell lineage.
Miller JC, Brown BD, Shay T, Gautier EL, Jojic V, Cohain A, Pandey G, Leboeuf M, Elpek KG, Helft J, Hashimoto D, Chow A, Price J, Greter M, Bogunovic M, Bellemare-Pelletier A, Frenette PS, Randolph GJ, Turley SJ, Merad M; Immunological Genome Consortium. Miller JC, et al. Among authors: randolph gj. Nat Immunol. 2012 Sep;13(9):888-99. doi: 10.1038/ni.2370. Epub 2012 Jul 15. Nat Immunol. 2012. PMID: 22797772 Free PMC article.
The role of the lymphatic system in cholesterol transport.
Huang LH, Elvington A, Randolph GJ. Huang LH, et al. Among authors: randolph gj. Front Pharmacol. 2015 Sep 2;6:182. doi: 10.3389/fphar.2015.00182. eCollection 2015. Front Pharmacol. 2015. PMID: 26388772 Free PMC article. Review.
Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.
Lu Q, Yokoyama CC, Williams JW, Baldridge MT, Jin X, DesRochers B, Bricker T, Wilen CB, Bagaitkar J, Loginicheva E, Sergushichev A, Kreamalmeyer D, Keller BC, Zhao Y, Kambal A, Green DR, Martinez J, Dinauer MC, Holtzman MJ, Crouch EC, Beatty W, Boon AC, Zhang H, Randolph GJ, Artyomov MN, Virgin HW. Lu Q, et al. Among authors: randolph gj. Cell Host Microbe. 2016 Jan 13;19(1):102-13. doi: 10.1016/j.chom.2015.12.011. Cell Host Microbe. 2016. PMID: 26764600 Free PMC article.
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Lampropoulou V, Sergushichev A, Bambouskova M, Nair S, Vincent EE, Loginicheva E, Cervantes-Barragan L, Ma X, Huang SC, Griss T, Weinheimer CJ, Khader S, Randolph GJ, Pearce EJ, Jones RG, Diwan A, Diamond MS, Artyomov MN. Lampropoulou V, et al. Among authors: randolph gj. Cell Metab. 2016 Jul 12;24(1):158-66. doi: 10.1016/j.cmet.2016.06.004. Epub 2016 Jun 30. Cell Metab. 2016. PMID: 27374498 Free PMC article.
Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models.
Kim K, Shim D, Lee JS, Zaitsev K, Williams JW, Kim KW, Jang MY, Seok Jang H, Yun TJ, Lee SH, Yoon WK, Prat A, Seidah NG, Choi J, Lee SP, Yoon SH, Nam JW, Seong JK, Oh GT, Randolph GJ, Artyomov MN, Cheong C, Choi JH. Kim K, et al. Among authors: randolph gj. Circ Res. 2018 Oct 26;123(10):1127-1142. doi: 10.1161/CIRCRESAHA.118.312804. Circ Res. 2018. PMID: 30359200 Free PMC article.
Cytokine Circuits in Cardiovascular Disease.
Williams JW, Huang LH, Randolph GJ. Williams JW, et al. Among authors: randolph gj. Immunity. 2019 Apr 16;50(4):941-954. doi: 10.1016/j.immuni.2019.03.007. Immunity. 2019. PMID: 30995508 Free PMC article. Review.
221 results