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Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, Duncan D, Bregman H, Keskin A, Santeford A, Apte RS, Sehgal R, Johnson B, Amarasinghe GK, Soares MP, Satoh T, Akira S, Hai T, de Guzman Strong C, Auclair K, Roddy TP, Biller SA, Jovanovic M, Klechevsky E, Stewart KM, Randolph GJ, Artyomov MN. Bambouskova M, et al. Among authors: satoh t. Nature. 2018 Apr;556(7702):501-504. doi: 10.1038/s41586-018-0052-z. Epub 2018 Apr 18. Nature. 2018. PMID: 29670287 Free PMC article.
Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency.
Yamamoto M, Uematsu S, Okamoto T, Matsuura Y, Sato S, Kumar H, Satoh T, Saitoh T, Takeda K, Ishii KJ, Takeuchi O, Kawai T, Akira S. Yamamoto M, et al. Among authors: satoh t. J Exp Med. 2007 Sep 3;204(9):2233-9. doi: 10.1084/jem.20070183. Epub 2007 Aug 27. J Exp Med. 2007. PMID: 17724128 Free PMC article.
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Saitoh T, et al. Among authors: satoh t. Nature. 2008 Nov 13;456(7219):264-8. doi: 10.1038/nature07383. Epub 2008 Oct 5. Nature. 2008. PMID: 18849965
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.
Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O. Satoh T, et al. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8. Proc Natl Acad Sci U S A. 2010. PMID: 20080593 Free PMC article.
IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18.
Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O. Miyake T, et al. Among authors: satoh t. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17680-5. doi: 10.1073/pnas.1012977107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876105 Free PMC article.
3,754 results