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Page 1
The biliary epithelium presents antigens to and activates natural killer T cells.
Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E. Schrumpf E, et al. Among authors: melum e. Hepatology. 2015 Oct;62(4):1249-59. doi: 10.1002/hep.27840. Epub 2015 May 20. Hepatology. 2015. PMID: 25855031 Free PMC article.
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J, Eksteen B, Ellinghaus D, Färkkilä M, Festen EAM, Floreani A, Franceschet I, Gotthardt DN, Hirschfield GM, Hoek BV, Holm K, Hohenester S, Hov JR, Imhann F, Invernizzi P, Juran BD, Lenzen H, Lieb W, Liu JZ, Marschall HU, Marzioni M, Melum E, Milkiewicz P, Müller T, Pares A, Rupp C, Rust C, Sandford RN, Schramm C, Schreiber S, Schrumpf E, Silverberg MS, Srivastava B, Sterneck M, Teufel A, Vallier L, Verheij J, Vila AV, Vries B, Zachou K; International PSC Study Group, The UK PSC Consortium; Chapman RW, Manns MP, Pinzani M, Rushbrook SM, Lazaridis KN, Franke A, Anderson CA, Karlsen TH, Ponsioen CY, Weersma RK. Alberts R, et al. Among authors: melum e. Gut. 2018 Aug;67(8):1517-1524. doi: 10.1136/gutjnl-2016-313598. Epub 2017 Aug 4. Gut. 2018. PMID: 28779025 Free PMC article.
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis.
Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E. Jiang X, et al. Among authors: melum e. Sci Transl Med. 2021 Feb 24;13(582):eabb0036. doi: 10.1126/scitranslmed.abb0036. Sci Transl Med. 2021. PMID: 33627483
Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma.
Zimmer CL, Filipovic I, Cornillet M, O'Rourke CJ, Berglin L, Jansson H, Sun D, Strauss O, Hertwig L, Johansson H, von Seth E, Sparrelid E, Dias J, Glaumann H, Melum E, Ellis EC, Sandberg JK, Andersen JB, Bergquist A, Björkström NK. Zimmer CL, et al. Among authors: melum e. Hepatology. 2022 May;75(5):1154-1168. doi: 10.1002/hep.32222. Epub 2021 Dec 22. Hepatology. 2022. PMID: 34719787
Cholangiocytes Modulate CD100 Expression in the Liver and Facilitate Pathogenic T-Helper 17 Cell Differentiation.
Jiang X, Otterdal K, Chung BK, Maucourant C, Rønneberg JD, Zimmer CL, Øgaard J, Boichuk Y, Holm S, Geanon D, Schneditz G, Bergquist A, Björkström NK, Melum E. Jiang X, et al. Among authors: melum e. Gastroenterology. 2024 Apr;166(4):667-679. doi: 10.1053/j.gastro.2023.11.283. Epub 2023 Nov 22. Gastroenterology. 2024. PMID: 37995866 Free article.
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