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Mechanisms of neutralization of a human anti-α-toxin antibody.
Oganesyan V, Peng L, Damschroder MM, Cheng L, Sadowska A, Tkaczyk C, Sellman BR, Wu H, Dall'Acqua WF. Oganesyan V, et al. Among authors: sadowska a. J Biol Chem. 2014 Oct 24;289(43):29874-80. doi: 10.1074/jbc.M114.601328. Epub 2014 Sep 10. J Biol Chem. 2014. PMID: 25210036 Free PMC article.
Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a Staphylococcus aureus dermonecrosis model.
Hilliard JJ, Datta V, Tkaczyk C, Hamilton M, Sadowska A, Jones-Nelson O, O'Day T, Weiss WJ, Szarka S, Nguyen V, Prokai L, Suzich J, Stover CK, Sellman BR. Hilliard JJ, et al. Among authors: sadowska a. Antimicrob Agents Chemother. 2015 Jan;59(1):299-309. doi: 10.1128/AAC.03918-14. Epub 2014 Oct 27. Antimicrob Agents Chemother. 2015. PMID: 25348518 Free PMC article.
Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease.
Tkaczyk C, Hamilton MM, Sadowska A, Shi Y, Chang CS, Chowdhury P, Buonapane R, Xiao X, Warrener P, Mediavilla J, Kreiswirth B, Suzich J, Stover CK, Sellman BR. Tkaczyk C, et al. Among authors: sadowska a. mBio. 2016 Jun 28;7(3):e00528-16. doi: 10.1128/mBio.00528-16. mBio. 2016. PMID: 27353753 Free PMC article.
Target-Agnostic Identification of Functional Monoclonal Antibodies Against Klebsiella pneumoniae Multimeric MrkA Fimbrial Subunit.
Wang Q, Chang CS, Pennini M, Pelletier M, Rajan S, Zha J, Chen Y, Cvitkovic R, Sadowska A, Heidbrink Thompson J, Yu Lin H, Barnes A, Rickert K, Wilson S, Stover CK, Dall'Acqua WF, Chowdhury PS, Xiao X. Wang Q, et al. Among authors: sadowska a. J Infect Dis. 2016 Jun 1;213(11):1800-8. doi: 10.1093/infdis/jiw021. Epub 2016 Jan 14. J Infect Dis. 2016. PMID: 26768253
Preclinical Characterization of an Antibody-Drug Conjugate Targeting CS-1 and the Identification of Uncharacterized Populations of CS-1-Positive Cells.
Chen R, Rajan S, Overstreet MG, Hurt EM, Thomas SB, Muniz-Medina V, Ward C, Sadowska A, Fleming R, Karanth S, Breen S, Zheng B, Wu Y, Iverson WO, Novick S, O'Day T, Shah DP, Dimasi N, Tiberghien AC, Osbourn J, Walker J. Chen R, et al. Among authors: sadowska a. Mol Cancer Ther. 2020 Aug;19(8):1649-1659. doi: 10.1158/1535-7163.MCT-19-0482. Epub 2020 May 13. Mol Cancer Ther. 2020. PMID: 32404408
Human Relaxin-2 Fusion Protein Treatment Prevents and Reverses Isoproterenol-Induced Hypertrophy and Fibrosis in Mouse Heart.
Sun J, Hao W, Fillmore N, Ma H, Springer D, Yu ZX, Sadowska A, Garcia A, Chen R, Muniz-Medina V, Rosenthal K, Lin J, Kuruvilla D, Osbourn J, Karathanasis SK, Walker J, Murphy E. Sun J, et al. Among authors: sadowska a. J Am Heart Assoc. 2019 Dec 17;8(24):e013465. doi: 10.1161/JAHA.119.013465. Epub 2019 Dec 10. J Am Heart Assoc. 2019. PMID: 31818212 Free PMC article.
146 results