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The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.
Durant ST, Zheng L, Wang Y, Chen K, Zhang L, Zhang T, Yang Z, Riches L, Trinidad AG, Fok JHL, Hunt T, Pike KG, Wilson J, Smith A, Colclough N, Reddy VP, Sykes A, Janefeldt A, Johnström P, Varnäs K, Takano A, Ling S, Orme J, Stott J, Roberts C, Barrett I, Jones G, Roudier M, Pierce A, Allen J, Kahn J, Sule A, Karlin J, Cronin A, Chapman M, Valerie K, Illingworth R, Pass M. Durant ST, et al. Among authors: kahn j. Sci Adv. 2018 Jun 20;4(6):eaat1719. doi: 10.1126/sciadv.aat1719. eCollection 2018 Jun. Sci Adv. 2018. PMID: 29938225 Free PMC article.
Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.
Karlin J, Allen J, Ahmad SF, Hughes G, Sheridan V, Odedra R, Farrington P, Cadogan EB, Riches LC, Garcia-Trinidad A, Thomason AG, Patel B, Vincent J, Lau A, Pike KG, Hunt TA, Sule A, Valerie NCK, Biddlestone-Thorpe L, Kahn J, Beckta JM, Mukhopadhyay N, Barlaam B, Degorce SL, Kettle J, Colclough N, Wilson J, Smith A, Barrett IP, Zheng L, Zhang T, Wang Y, Chen K, Pass M, Durant ST, Valerie K. Karlin J, et al. Among authors: kahn j. Mol Cancer Ther. 2018 Aug;17(8):1637-1647. doi: 10.1158/1535-7163.MCT-17-0975. Epub 2018 May 16. Mol Cancer Ther. 2018. PMID: 29769307 Free PMC article.
Preclinical models in radiation oncology.
Kahn J, Tofilon PJ, Camphausen K. Kahn J, et al. Radiat Oncol. 2012 Dec 27;7:223. doi: 10.1186/1748-717X-7-223. Radiat Oncol. 2012. PMID: 23270380 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 34700866
Integrating Radiation Oncology Into Undergraduate Medical Education.
Arbab M, Holmes JA, Olivier KR, Fields EC, Corbin KS, Kahn JM, Zellars RC, Haywood AM. Arbab M, et al. Adv Radiat Oncol. 2021 Jul 28;6(6):100765. doi: 10.1016/j.adro.2021.100765. eCollection 2021 Nov-Dec. Adv Radiat Oncol. 2021. PMID: 34522827 Free PMC article.
2,818 results