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Page 1
Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms.
Tsujimoto S, Osumi T, Uchiyama M, Shirai R, Moriyama T, Nishii R, Yamada Y, Kudo K, Sekiguchi M, Arakawa Y, Yoshida M, Uchiyama T, Terui K, Ito S, Koh K, Takita J, Ito E, Tomizawa D, Manabe A, Kiyokawa N, Yang JJ, Kato M. Tsujimoto S, et al. Among authors: yang jj. Leukemia. 2018 Dec;32(12):2710-2714. doi: 10.1038/s41375-018-0190-1. Epub 2018 Jul 2. Leukemia. 2018. PMID: 29967377 Free PMC article. No abstract available.
Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study.
Moriyama T, Metzger ML, Wu G, Nishii R, Qian M, Devidas M, Yang W, Cheng C, Cao X, Quinn E, Raimondi S, Gastier-Foster JM, Raetz E, Larsen E, Martin PL, Bowman WP, Winick N, Komada Y, Wang S, Edmonson M, Xu H, Mardis E, Fulton R, Pui CH, Mullighan C, Evans WE, Zhang J, Hunger SP, Relling MV, Nichols KE, Loh ML, Yang JJ. Moriyama T, et al. Among authors: yang jj, yang w. Lancet Oncol. 2015 Dec;16(16):1659-66. doi: 10.1016/S1470-2045(15)00369-1. Epub 2015 Oct 28. Lancet Oncol. 2015. PMID: 26522332 Free PMC article.
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.
Moriyama T, Nishii R, Perez-Andreu V, Yang W, Klussmann FA, Zhao X, Lin TN, Hoshitsuki K, Nersting J, Kihira K, Hofmann U, Komada Y, Kato M, McCorkle R, Li L, Koh K, Najera CR, Kham SK, Isobe T, Chen Z, Chiew EK, Bhojwani D, Jeffries C, Lu Y, Schwab M, Inaba H, Pui CH, Relling MV, Manabe A, Hori H, Schmiegelow K, Yeoh AE, Evans WE, Yang JJ. Moriyama T, et al. Among authors: yang jj, yang w. Nat Genet. 2016 Apr;48(4):367-73. doi: 10.1038/ng.3508. Epub 2016 Feb 15. Nat Genet. 2016. PMID: 26878724 Free PMC article.
Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry.
Moriyama T, Yang YL, Nishii R, Ariffin H, Liu C, Lin TN, Yang W, Lin DT, Yu CH, Kham S, Pui CH, Evans WE, Jeha S, Relling MV, Yeoh AE, Yang JJ. Moriyama T, et al. Among authors: yang yl, yang jj, yang w. Blood. 2017 Sep 7;130(10):1209-1212. doi: 10.1182/blood-2017-05-782383. Epub 2017 Jun 28. Blood. 2017. PMID: 28659275 Free PMC article.
Combination of common and novel rare NUDT15 variants improves predictive sensitivity of thiopurine-induced leukopenia in children with acute lymphoblastic leukemia.
Zhu Y, Yin D, Su Y, Xia X, Moriyama T, Nishii R, Liao F, Zhang S, Guo X, Hou Q, Ai Y, Zhou X, Sun S, Zhang D, Zhang Y, Lin C, Deng Y, Lu X, Wang Y, Ma Z, Wang H, Liu B, Yang L, Zhang W, Yang JJ, Shu Y, Gao J, Xu H. Zhu Y, et al. Among authors: yang l, yang jj. Haematologica. 2018 Jul;103(7):e293-e295. doi: 10.3324/haematol.2018.187658. Epub 2018 Mar 8. Haematologica. 2018. PMID: 29519865 Free PMC article. No abstract available.
Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy.
Nishii R, Moriyama T, Janke LJ, Yang W, Suiter CC, Lin TN, Li L, Kihira K, Toyoda H, Hofmann U, Schwab M, Takagi M, Morio T, Manabe A, Kham S, Jiang N, Rabin KR, Kato M, Koh K, Yeoh AE, Hori H, Yang JJ. Nishii R, et al. Among authors: yang jj, yang w. Blood. 2018 May 31;131(22):2466-2474. doi: 10.1182/blood-2017-11-815506. Epub 2018 Mar 23. Blood. 2018. PMID: 29572377 Free PMC article.
Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update.
Relling MV, Schwab M, Whirl-Carrillo M, Suarez-Kurtz G, Pui CH, Stein CM, Moyer AM, Evans WE, Klein TE, Antillon-Klussmann FG, Caudle KE, Kato M, Yeoh AEJ, Schmiegelow K, Yang JJ. Relling MV, et al. Among authors: yang jj. Clin Pharmacol Ther. 2019 May;105(5):1095-1105. doi: 10.1002/cpt.1304. Epub 2019 Jan 20. Clin Pharmacol Ther. 2019. PMID: 30447069 Free PMC article.
2,202 results