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Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure.
DeLalio LJ, Keller AS, Chen J, Boyce AKJ, Artamonov MV, Askew-Page HR, Keller TCS 4th, Johnstone SR, Weaver RB, Good ME, Murphy SA, Best AK, Mintz EL, Penuela S, Greenwood IA, Machado RF, Somlyo AV, Swayne LA, Minshall RD, Isakson BE. DeLalio LJ, et al. Among authors: machado rf. Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2065-2078. doi: 10.1161/ATVBAHA.118.311290. Arterioscler Thromb Vasc Biol. 2018. PMID: 30026274 Free PMC article.
Upregulated copper transporters in hypoxia-induced pulmonary hypertension.
Zimnicka AM, Tang H, Guo Q, Kuhr FK, Oh MJ, Wan J, Chen J, Smith KA, Fraidenburg DR, Choudhury MS, Levitan I, Machado RF, Kaplan JH, Yuan JX. Zimnicka AM, et al. Among authors: machado rf. PLoS One. 2014 Mar 10;9(3):e90544. doi: 10.1371/journal.pone.0090544. eCollection 2014. PLoS One. 2014. PMID: 24614111 Free PMC article.
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX. Tang H, et al. Among authors: machado rf. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L208-20. doi: 10.1152/ajplung.00242.2014. Epub 2014 Nov 21. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25416384 Free PMC article.
Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-β-driven pulmonary vascular remodeling.
Oliveira SDS, Castellon M, Chen J, Bonini MG, Gu X, Elliott MH, Machado RF, Minshall RD. Oliveira SDS, et al. Among authors: machado rf. Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L760-L771. doi: 10.1152/ajplung.00484.2016. Epub 2017 Feb 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28188225 Free PMC article.
Loss of lung WWOX expression causes neutrophilic inflammation.
Singla S, Chen J, Sethuraman S, Sysol JR, Gampa A, Zhao S, Machado RF. Singla S, et al. Among authors: machado rf. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L903-L911. doi: 10.1152/ajplung.00034.2017. Epub 2017 Mar 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28283473 Free PMC article.
Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary Hypertension.
Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd JE, Austin ED, Machado RF, Minshall RD, Rehman J, Malik AB. Marsboom G, et al. Among authors: machado rf. Mol Biol Cell. 2017 Mar 15:mbc.E16-06-0380. doi: 10.1091/mbc.E16-06-0380. Online ahead of print. Mol Biol Cell. 2017. PMID: 28298490
167 results