Edwards AB - Search Results

1

Perinatal Hypoxic-Ischemic Encephalopathy and Neuroprotective Peptide Therapies: A Case for Cationic Arginine-Rich Peptides (CARPs).

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. Edwards AB, et al. Brain Sci. 2018 Aug 7;8(8):147. doi: 10.3390/brainsci8080147. Brain Sci. 2018. PMID: 30087289 Free PMC article. Review.

2

Poly-arginine and arginine-rich peptides are neuroprotective in stroke models.

Meloni BP, Brookes LM, Clark VW, Cross JL, Edwards AB, Anderton RS, Hopkins RM, Hoffmann K, Knuckey NW. Meloni BP, et al. Among authors: edwards ab. J Cereb Blood Flow Metab. 2015 Jun;35(6):993-1004. doi: 10.1038/jcbfm.2015.11. Epub 2015 Feb 11. J Cereb Blood Flow Metab. 2015. PMID: 25669902 Free PMC article.

3

Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties.

Meloni BP, Milani D, Edwards AB, Anderton RS, O'Hare Doig RL, Fitzgerald M, Palmer TN, Knuckey NW. Meloni BP, et al. Among authors: edwards ab. Pharmacol Ther. 2015 Sep;153:36-54. doi: 10.1016/j.pharmthera.2015.06.002. Epub 2015 Jun 3. Pharmacol Ther. 2015. PMID: 26048328 Review.

4

Characterisation of neuroprotective efficacy of modified poly-arginine-9 (R9) peptides using a neuronal glutamic acid excitotoxicity model.

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. Edwards AB, et al. Mol Cell Biochem. 2017 Feb;426(1-2):75-85. doi: 10.1007/s11010-016-2882-z. Epub 2016 Nov 14. Mol Cell Biochem. 2017. PMID: 27844251

5

Assessment of the Neuroprotective Effects of Arginine-Rich Protamine Peptides, Poly-Arginine Peptides (R12-Cyclic, R22) and Arginine-Tryptophan-Containing Peptides Following In Vitro Excitotoxicity and/or Permanent Middle Cerebral Artery Occlusion in Rats.

Meloni BP, Milani D, Cross JL, Clark VW, Edwards AB, Anderton RS, Blacker DJ, Knuckey NW. Meloni BP, et al. Among authors: edwards ab. Neuromolecular Med. 2017 Sep;19(2-3):271-285. doi: 10.1007/s12017-017-8441-2. Epub 2017 May 18. Neuromolecular Med. 2017. PMID: 28523591

6

Poly-arginine R18 and R18D (D-enantiomer) peptides reduce infarct volume and improves behavioural outcomes following perinatal hypoxic-ischaemic encephalopathy in the P7 rat.

Edwards AB, Cross JL, Anderton RS, Knuckey NW, Meloni BP. Edwards AB, et al. Mol Brain. 2018 Feb 9;11(1):8. doi: 10.1186/s13041-018-0352-0. Mol Brain. 2018. PMID: 29426351 Free PMC article.

7

Assessment of therapeutic window for poly-arginine-18D (R18D) in a P7 rat model of perinatal hypoxic-ischaemic encephalopathy.

Edwards AB, Anderton RS, Knuckey NW, Meloni BP. Edwards AB, et al. J Neurosci Res. 2018 Nov;96(11):1816-1826. doi: 10.1002/jnr.24315. Epub 2018 Aug 26. J Neurosci Res. 2018. PMID: 30146697

8

Neuroprotective Cationic Arginine-Rich Peptides (CARPs): An Assessment of Their Clinical Safety.

Edwards AB, Mastaglia FL, Knuckey NW, Meloni BP. Edwards AB, et al. Drug Saf. 2020 Oct;43(10):957-969. doi: 10.1007/s40264-020-00962-z. Drug Saf. 2020. PMID: 32613595 Review.

9

Assessment of the safety of the cationic arginine-rich peptides (CARPs) poly-arginine-18 (R18 and R18D) in ex vivo models of mast cell degranulation and red blood cell hemolysis.

Edwards AB, Mastaglia FL, Knuckey NW, Yip KH, Meloni B. Edwards AB, et al. Biochem Biophys Rep. 2022 Jul 1;31:101305. doi: 10.1016/j.bbrep.2022.101305. eCollection 2022 Sep. Biochem Biophys Rep. 2022. PMID: 35812346 Free PMC article.

10

The Neuroprotective Peptide Poly-Arginine-12 (R12) Reduces Cell Surface Levels of NMDA NR2B Receptor Subunit in Cortical Neurons; Investigation into the Involvement of Endocytic Mechanisms.

MacDougall G, Anderton RS, Edwards AB, Knuckey NW, Meloni BP. MacDougall G, et al. Among authors: edwards ab. J Mol Neurosci. 2017 Feb;61(2):235-246. doi: 10.1007/s12031-016-0861-1. Epub 2016 Nov 20. J Mol Neurosci. 2017. PMID: 27866326

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