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Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Walters LC, Harlos K, Brackenridge S, Rozbesky D, Barrett JR, Jain V, Walter TS, O'Callaghan CA, Borrow P, Toebes M, Hansen SG, Sacha JB, Abdulhaqq S, Greene JM, Früh K, Marshall E, Picker LJ, Jones EY, McMichael AJ, Gillespie GM. Walters LC, et al. Among authors: fruh k. Nat Commun. 2018 Aug 7;9(1):3137. doi: 10.1038/s41467-018-05459-z. Nat Commun. 2018. PMID: 30087334 Free PMC article.
Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.
Hansen SG, Powers CJ, Richards R, Ventura AB, Ford JC, Siess D, Axthelm MK, Nelson JA, Jarvis MA, Picker LJ, Früh K. Hansen SG, et al. Among authors: fruh k. Science. 2010 Apr 2;328(5974):102-6. doi: 10.1126/science.1185350. Science. 2010. PMID: 20360110 Free PMC article.
Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms.
Hansen SG, Sacha JB, Hughes CM, Ford JC, Burwitz BJ, Scholz I, Gilbride RM, Lewis MS, Gilliam AN, Ventura AB, Malouli D, Xu G, Richards R, Whizin N, Reed JS, Hammond KB, Fischer M, Turner JM, Legasse AW, Axthelm MK, Edlefsen PT, Nelson JA, Lifson JD, Früh K, Picker LJ. Hansen SG, et al. Among authors: fruh k. Science. 2013 May 24;340(6135):1237874. doi: 10.1126/science.1237874. Science. 2013. PMID: 23704576 Free PMC article.
Immune clearance of highly pathogenic SIV infection.
Hansen SG, Piatak M Jr, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, Turner JM, Legasse AW, Axthelm MK, Nelson JA, Früh K, Sacha JB, Estes JD, Keele BF, Edlefsen PT, Lifson JD, Picker LJ. Hansen SG, et al. Among authors: fruh k. Nature. 2013 Oct 3;502(7469):100-4. doi: 10.1038/nature12519. Epub 2013 Sep 11. Nature. 2013. PMID: 24025770 Free PMC article.
Cytomegalovirus pp65 limits dissemination but is dispensable for persistence.
Malouli D, Hansen SG, Nakayasu ES, Marshall EE, Hughes CM, Ventura AB, Gilbride RM, Lewis MS, Xu G, Kreklywich C, Whizin N, Fischer M, Legasse AW, Viswanathan K, Siess D, Camp DG 2nd, Axthelm MK, Kahl C, DeFilippis VR, Smith RD, Streblow DN, Picker LJ, Früh K. Malouli D, et al. Among authors: fruh k. J Clin Invest. 2014 May;124(5):1928-44. doi: 10.1172/JCI67420. Epub 2014 Apr 1. J Clin Invest. 2014. PMID: 24691437 Free PMC article.
T cell inactivation by poxviral B22 family proteins increases viral virulence.
Alzhanova D, Hammarlund E, Reed J, Meermeier E, Rawlings S, Ray CA, Edwards DM, Bimber B, Legasse A, Planer S, Sprague J, Axthelm MK, Pickup DJ, Lewinsohn DM, Gold MC, Wong SW, Sacha JB, Slifka MK, Früh K. Alzhanova D, et al. Among authors: fruh k. PLoS Pathog. 2014 May 15;10(5):e1004123. doi: 10.1371/journal.ppat.1004123. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24832205 Free PMC article.
161 results