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Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.
Ralvenius WT, Neumann E, Pagani M, Acuña MA, Wildner H, Benke D, Fischer N, Rostaher A, Schwager S, Detmar M, Frauenknecht K, Aguzzi A, Hubbs JL, Rudolph U, Favrot C, Zeilhofer HU. Ralvenius WT, et al. Among authors: acuna ma. Nat Commun. 2018 Aug 13;9(1):3230. doi: 10.1038/s41467-018-05709-0. Nat Commun. 2018. PMID: 30104684 Free PMC article.
Mice lacking spinal α2GABAA receptors: Altered GABAergic neurotransmission, diminished GABAergic antihyperalgesia, and potential compensatory mechanisms preventing a hyperalgesic phenotype.
Tudeau L, Acuña MA, Albisetti GW, Neumann E, Ralvenius WT, Scheurer L, Poe M, Cook JM, Johannssen HC, Zeilhofer HU. Tudeau L, et al. Among authors: acuna ma. Brain Res. 2020 Aug 15;1741:146889. doi: 10.1016/j.brainres.2020.146889. Epub 2020 May 18. Brain Res. 2020. PMID: 32439345 Free article.
Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface γ-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CHOP).
Maier PJ, Zemoura K, Acuña MA, Yévenes GE, Zeilhofer HU, Benke D. Maier PJ, et al. Among authors: acuna ma. J Biol Chem. 2014 May 2;289(18):12896-907. doi: 10.1074/jbc.M114.550517. Epub 2014 Mar 25. J Biol Chem. 2014. PMID: 24668805 Free PMC article.
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