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The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor.
García-Nicolás O, V'kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S. García-Nicolás O, et al. Among authors: pietschmann t. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01206-18. doi: 10.1128/AAC.01206-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30181371 Free PMC article.
Hepatocytes that express variants of cyclophilin A are resistant to HCV infection and replication.
von Hahn T, Schiene-Fischer C, Van ND, Pfaender S, Karavul B, Steinmann E, Potthoff A, Strassburg C, Hamdi N, Abdelaziz AI, Sarrazin C, Müller T, Berg T, Trépo E, Wedemeyer H, Manns MP, Pietschmann T, Ciesek S. von Hahn T, et al. Among authors: pietschmann t. Gastroenterology. 2012 Aug;143(2):439-47.e1. doi: 10.1053/j.gastro.2012.04.053. Epub 2012 May 8. Gastroenterology. 2012. PMID: 22580540
hepatitis c Virus p7 is critical for capsid assembly and envelopment.
Gentzsch J, Brohm C, Steinmann E, Friesland M, Menzel N, Vieyres G, Perin PM, Frentzen A, Kaderali L, Pietschmann T. Gentzsch J, et al. Among authors: pietschmann t. PLoS Pathog. 2013;9(5):e1003355. doi: 10.1371/journal.ppat.1003355. Epub 2013 May 2. PLoS Pathog. 2013. PMID: 23658526 Free PMC article.
Thermostability of seven hepatitis C virus genotypes in vitro and in vivo.
Doerrbecker J, Meuleman P, Kang J, Riebesehl N, Wilhelm C, Friesland M, Pfaender S, Steinmann J, Pietschmann T, Steinmann E. Doerrbecker J, et al. Among authors: pietschmann t. J Viral Hepat. 2013 Jul;20(7):478-85. doi: 10.1111/jvh.12055. Epub 2013 Jan 17. J Viral Hepat. 2013. PMID: 23730841 Free article.
Inactivation of hepatitis C virus infectivity by human breast milk.
Pfaender S, Heyden J, Friesland M, Ciesek S, Ejaz A, Steinmann J, Steinmann J, Malarski A, Stoiber H, Tsiavaliaris G, Bader W, Jahreis G, Pietschmann T, Steinmann E. Pfaender S, et al. Among authors: pietschmann t. J Infect Dis. 2013 Dec 15;208(12):1943-52. doi: 10.1093/infdis/jit519. Epub 2013 Sep 24. J Infect Dis. 2013. PMID: 24068703
211 results