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Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.
Whitaker-Menezes D, Martinez-Outschoorn UE, Lin Z, Ertel A, Flomenberg N, Witkiewicz AK, Birbe RC, Howell A, Pavlides S, Gandara R, Pestell RG, Sotgia F, Philp NJ, Lisanti MP. Whitaker-Menezes D, et al. Among authors: philp nj. Cell Cycle. 2011 Jun 1;10(11):1772-83. doi: 10.4161/cc.10.11.15659. Epub 2011 Jun 1. Cell Cycle. 2011. PMID: 21558814 Free PMC article.
Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
Witkiewicz AK, Whitaker-Menezes D, Dasgupta A, Philp NJ, Lin Z, Gandara R, Sneddon S, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Witkiewicz AK, et al. Among authors: philp nj. Cell Cycle. 2012 Mar 15;11(6):1108-17. doi: 10.4161/cc.11.6.19530. Epub 2012 Mar 15. Cell Cycle. 2012. PMID: 22313602 Free PMC article.
Metformin Clinical Trial in HPV+ and HPV- Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate.
Curry JM, Johnson J, Mollaee M, Tassone P, Amin D, Knops A, Whitaker-Menezes D, Mahoney MG, South A, Rodeck U, Zhan T, Harshyne L, Philp N, Luginbuhl A, Cognetti D, Tuluc M, Martinez-Outschoorn U. Curry JM, et al. Front Oncol. 2018 Oct 11;8:436. doi: 10.3389/fonc.2018.00436. eCollection 2018. Front Oncol. 2018. PMID: 30364350 Free PMC article.
89 results