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The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival.
Santegoets SJ, van Ham VJ, Ehsan I, Charoentong P, Duurland CL, van Unen V, Höllt T, van der Velden LA, van Egmond SL, Kortekaas KE, de Vos van Steenwijk PJ, van Poelgeest MIE, Welters MJP, van der Burg SH. Santegoets SJ, et al. Among authors: charoentong p. Clin Cancer Res. 2019 Jan 1;25(1):240-252. doi: 10.1158/1078-0432.CCR-18-1749. Epub 2018 Sep 17. Clin Cancer Res. 2019. PMID: 30224343
Intratumoral HPV16-Specific T Cells Constitute a Type I-Oriented Tumor Microenvironment to Improve Survival in HPV16-Driven Oropharyngeal Cancer.
Welters MJP, Ma W, Santegoets SJAM, Goedemans R, Ehsan I, Jordanova ES, van Ham VJ, van Unen V, Koning F, van Egmond SI, Charoentong P, Trajanoski Z, van der Velden LA, van der Burg SH. Welters MJP, et al. Among authors: charoentong p. Clin Cancer Res. 2018 Feb 1;24(3):634-647. doi: 10.1158/1078-0432.CCR-17-2140. Epub 2017 Oct 10. Clin Cancer Res. 2018. PMID: 29018052
NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines.
van Montfoort N, Borst L, Korrer MJ, Sluijter M, Marijt KA, Santegoets SJ, van Ham VJ, Ehsan I, Charoentong P, André P, Wagtmann N, Welters MJP, Kim YJ, Piersma SJ, van der Burg SH, van Hall T. van Montfoort N, et al. Among authors: charoentong p. Cell. 2018 Dec 13;175(7):1744-1755.e15. doi: 10.1016/j.cell.2018.10.028. Epub 2018 Nov 29. Cell. 2018. PMID: 30503208 Free PMC article.
Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy.
Kortekaas KE, Santegoets SJ, Tas L, Ehsan I, Charoentong P, van Doorn HC, van Poelgeest MIE, Mustafa DAM, van der Burg SH. Kortekaas KE, et al. Among authors: charoentong p. J Immunother Cancer. 2021 Oct;9(10):e003671. doi: 10.1136/jitc-2021-003671. J Immunother Cancer. 2021. PMID: 34716208 Free PMC article.
NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division.
Borst L, Sluijter M, Sturm G, Charoentong P, Santegoets SJ, van Gulijk M, van Elsas MJ, Groeneveldt C, van Montfoort N, Finotello F, Trajanoski Z, Kiełbasa SM, van der Burg SH, van Hall T. Borst L, et al. Among authors: charoentong p. Int J Cancer. 2022 Feb 15;150(4):688-704. doi: 10.1002/ijc.33859. Epub 2021 Nov 10. Int J Cancer. 2022. PMID: 34716584 Free PMC article.
Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival.
Abdulrahman Z, Santegoets SJ, Sturm G, Charoentong P, Ijsselsteijn ME, Somarakis A, Höllt T, Finotello F, Trajanoski Z, van Egmond SL, Mustafa DAM, Welters MJP, de Miranda NFCC, van der Burg SH. Abdulrahman Z, et al. Among authors: charoentong p. J Immunother Cancer. 2022 Feb;10(2):e004346. doi: 10.1136/jitc-2021-004346. J Immunother Cancer. 2022. PMID: 35217577 Free PMC article.
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman WH, Galon J. Camus M, et al. Among authors: charoentong p. Cancer Res. 2009 Mar 15;69(6):2685-93. doi: 10.1158/0008-5472.CAN-08-2654. Epub 2009 Mar 3. Cancer Res. 2009. PMID: 19258510
In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer.
Kather JN, Poleszczuk J, Suarez-Carmona M, Krisam J, Charoentong P, Valous NA, Weis CA, Tavernar L, Leiss F, Herpel E, Klupp F, Ulrich A, Schneider M, Marx A, Jäger D, Halama N. Kather JN, et al. Among authors: charoentong p. Cancer Res. 2017 Nov 15;77(22):6442-6452. doi: 10.1158/0008-5472.CAN-17-2006. Epub 2017 Sep 18. Cancer Res. 2017. PMID: 28923860 Free article.
High-Throughput Screening of Combinatorial Immunotherapies with Patient-Specific In Silico Models of Metastatic Colorectal Cancer.
Kather JN, Charoentong P, Suarez-Carmona M, Herpel E, Klupp F, Ulrich A, Schneider M, Zoernig I, Luedde T, Jaeger D, Poleszczuk J, Halama N. Kather JN, et al. Among authors: charoentong p. Cancer Res. 2018 Sep 1;78(17):5155-5163. doi: 10.1158/0008-5472.CAN-18-1126. Epub 2018 Jul 2. Cancer Res. 2018. PMID: 29967263 Free article.
38 results