Lyumkis D - Search Results

1

Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.

Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D. Zhang C, et al. Among authors: lyumkis d. Cell. 2018 Sep 20;175(1):212-223.e17. doi: 10.1016/j.cell.2018.09.001. Cell. 2018. PMID: 30241607 Free PMC article.

2

Structural Basis for the Activation of IKK1/α.

Polley S, Passos DO, Huang DB, Mulero MC, Mazumder A, Biswas T, Verma IM, Lyumkis D, Ghosh G. Polley S, et al. Among authors: lyumkis d. Cell Rep. 2016 Nov 15;17(8):1907-1914. doi: 10.1016/j.celrep.2016.10.067. Cell Rep. 2016. PMID: 27851956 Free PMC article.

3

Analysis of discrete local variability and structural covariance in macromolecular assemblies using Cryo-EM and focused classification.

Zhang C, Cantara W, Jeon Y, Musier-Forsyth K, Grigorieff N, Lyumkis D. Zhang C, et al. Among authors: lyumkis d. Ultramicroscopy. 2019 Aug;203:170-180. doi: 10.1016/j.ultramic.2018.11.016. Epub 2018 Nov 29. Ultramicroscopy. 2019. PMID: 30528101 Free PMC article.

4

Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA.

Haack DB, Yan X, Zhang C, Hingey J, Lyumkis D, Baker TS, Toor N. Haack DB, et al. Among authors: lyumkis d. Cell. 2019 Jul 25;178(3):612-623.e12. doi: 10.1016/j.cell.2019.06.035. Cell. 2019. PMID: 31348888 Free PMC article.

5

Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd.

Brugger C, Zhang C, Suhanovsky MM, Kim DD, Sinclair AN, Lyumkis D, Deaconescu AM. Brugger C, et al. Among authors: lyumkis d. Nat Commun. 2020 Jul 27;11(1):3740. doi: 10.1038/s41467-020-17457-1. Nat Commun. 2020. PMID: 32719356 Free PMC article.

6

Evaluating Local and Directional Resolution of Cryo-EM Density Maps.

Aiyer S, Zhang C, Baldwin PR, Lyumkis D. Aiyer S, et al. Among authors: lyumkis d. Methods Mol Biol. 2021;2215:161-187. doi: 10.1007/978-1-0716-0966-8_8. Methods Mol Biol. 2021. PMID: 33368004 Free PMC article.

7

Single-Particle Cryo-EM Data Collection with Stage Tilt using Leginon.

Aiyer S, Strutzenberg TS, Bowman ME, Noel JP, Lyumkis D. Aiyer S, et al. Among authors: lyumkis d. J Vis Exp. 2022 Jul 1;(185):10.3791/64136. doi: 10.3791/64136. J Vis Exp. 2022. PMID: 35848829 Free PMC article.

8

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.

Li M, Oliveira Passos D, Shan Z, Smith SJ, Sun Q, Biswas A, Choudhuri I, Strutzenberg TS, Haldane A, Deng N, Li Z, Zhao XZ, Briganti L, Kvaratskhelia M, Burke TR Jr, Levy RM, Hughes SH, Craigie R, Lyumkis D. Li M, et al. Among authors: lyumkis d. Sci Adv. 2023 Jul 21;9(29):eadg5953. doi: 10.1126/sciadv.adg5953. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478179 Free article.

9

Anisotropy in CryoEM Resolution is Dominated by Preferred Orientations, but not Structure Factors: A Study Using a Highly Symmetric Structure.

Baldwin PR, Aiyer S, Strutzenberg TS, Lyumkis D. Baldwin PR, et al. Among authors: lyumkis d. Microsc Microanal. 2023 Jul 22;29(29 Suppl 1):1021-1023. doi: 10.1093/micmic/ozad067.517. Microsc Microanal. 2023. PMID: 37613383 No abstract available.

10

Structural basis of branching during RNA splicing.

Haack DB, Rudolfs B, Zhang C, Lyumkis D, Toor N. Haack DB, et al. Among authors: lyumkis d. Nat Struct Mol Biol. 2024 Jan;31(1):179-189. doi: 10.1038/s41594-023-01150-0. Epub 2023 Dec 6. Nat Struct Mol Biol. 2024. PMID: 38057551 Free PMC article.

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