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The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy.
Chan JF, Zhu Z, Chu H, Yuan S, Chik KK, Chan CC, Poon VK, Yip CC, Zhang X, Tsang JO, Zou Z, Tee KM, Shuai H, Lu G, Yuen KY. Chan JF, et al. Among authors: lu g. Antiviral Res. 2018 Dec;160:38-47. doi: 10.1016/j.antiviral.2018.10.007. Epub 2018 Oct 13. Antiviral Res. 2018. PMID: 30326204 Free PMC article.
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.
Chan JF, Yip CC, Tsang JO, Tee KM, Cai JP, Chik KK, Zhu Z, Chan CC, Choi GK, Sridhar S, Zhang AJ, Lu G, Chiu K, Lo AC, Tsao SW, Kok KH, Jin DY, Chan KH, Yuen KY. Chan JF, et al. Among authors: lu g. Emerg Microbes Infect. 2016 Aug 24;5(8):e93. doi: 10.1038/emi.2016.99. Emerg Microbes Infect. 2016. PMID: 27553173 Free PMC article.
Development and in-use evaluation of a novel Luminex MicroPlex microsphere-based (TRIOL) assay for simultaneous identification of Mycobacterium tuberculosis and detection of first-line and second-line anti-tuberculous drug resistance in China.
Yin F, Chan JF, Zhu Q, Fu R, Chen JH, Choi GK, Tee KM, Li L, Qian S, Yam WC, Lu G, Yuen KY. Yin F, et al. Among authors: lu g. J Clin Pathol. 2017 Apr;70(4):342-349. doi: 10.1136/jclinpath-2016-203952. Epub 2016 Sep 19. J Clin Pathol. 2017. PMID: 27646524
Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system.
Yuan S, Chan JFW, Chik KKH, Chan CCY, Tsang JOL, Liang R, Cao J, Tang K, Chen LL, Wen K, Cai JP, Ye ZW, Lu G, Chu H, Jin DY, Yuen KY. Yuan S, et al. Among authors: lu g. Pharmacol Res. 2020 Sep;159:104960. doi: 10.1016/j.phrs.2020.104960. Epub 2020 May 28. Pharmacol Res. 2020. PMID: 32473310 Free PMC article.
STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells.
Yang D, Chu H, Lu G, Shuai H, Wang Y, Hou Y, Zhang X, Huang X, Hu B, Chai Y, Yuen TT, Zhao X, Lee AC, Ye Z, Li C, Chik KK, Zhang AJ, Zhou J, Yuan S, Chan JF. Yang D, et al. Among authors: lu g. Emerg Microbes Infect. 2021 Dec;10(1):1024-1037. doi: 10.1080/22221751.2021.1929503. Emerg Microbes Infect. 2021. PMID: 33979266 Free PMC article.
8,081 results