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931 results

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Sotatercept, a novel transforming growth factor β ligand trap, improves anemia in β-thalassemia: a phase II, open-label, dose-finding study.
Cappellini MD, Porter J, Origa R, Forni GL, Voskaridou E, Galactéros F, Taher AT, Arlet JB, Ribeil JA, Garbowski M, Graziadei G, Brouzes C, Semeraro M, Laadem A, Miteva D, Zou J, Sung V, Zinger T, Attie KM, Hermine O. Cappellini MD, et al. Among authors: hermine o. Haematologica. 2019 Mar;104(3):477-484. doi: 10.3324/haematol.2018.198887. Epub 2018 Oct 18. Haematologica. 2019. PMID: 30337358 Free PMC article. Clinical Trial.
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1.
Ribeil JA, Zermati Y, Vandekerckhove J, Cathelin S, Kersual J, Dussiot M, Coulon S, Moura IC, Zeuner A, Kirkegaard-Sørensen T, Varet B, Solary E, Garrido C, Hermine O. Ribeil JA, et al. Among authors: hermine o. Nature. 2007 Jan 4;445(7123):102-5. doi: 10.1038/nature05378. Epub 2006 Dec 10. Nature. 2007. PMID: 17167422
Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of glucosylceramide synthase activity.
Dbaibo GS, Kfoury Y, Darwiche N, Panjarian S, Kozhaya L, Nasr R, Abdallah M, Hermine O, El-Sabban M, de Thé H, Bazarbachi A. Dbaibo GS, et al. Among authors: hermine o. Haematologica. 2007 Jun;92(6):753-62. doi: 10.3324/haematol.10968. Haematologica. 2007. PMID: 17550847 Free article.
[Hsp 70, guardian angel of GATA-1 during erythroid differentiation].
Vandekerckhove J, Ribeil JA, Zermati Y, Garrido C, Courtois G, Solary E, Hermine O. Vandekerckhove J, et al. Among authors: hermine o. Med Sci (Paris). 2008 Jan;24(1):37-40. doi: 10.1051/medsci/200824137. Med Sci (Paris). 2008. PMID: 18198108 Free article. French. No abstract available.
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.
Coulon S, Dussiot M, Grapton D, Maciel TT, Wang PH, Callens C, Tiwari MK, Agarwal S, Fricot A, Vandekerckhove J, Tamouza H, Zermati Y, Ribeil JA, Djedaini K, Oruc Z, Pascal V, Courtois G, Arnulf B, Alyanakian MA, Mayeux P, Leanderson T, Benhamou M, Cogné M, Monteiro RC, Hermine O, Moura IC. Coulon S, et al. Among authors: hermine o. Nat Med. 2011 Oct 23;17(11):1456-65. doi: 10.1038/nm.2462. Nat Med. 2011. PMID: 22019886
Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes.
Frisan E, Vandekerckhove J, de Thonel A, Pierre-Eugène C, Sternberg A, Arlet JB, Floquet C, Gyan E, Kosmider O, Dreyfus F, Gabet AS, Courtois G, Vyas P, Ribeil JA, Zermati Y, Lacombe C, Mayeux P, Solary E, Garrido C, Hermine O, Fontenay M. Frisan E, et al. Among authors: hermine o. Blood. 2012 Feb 9;119(6):1532-42. doi: 10.1182/blood-2011-03-343475. Epub 2011 Dec 12. Blood. 2012. PMID: 22160620 Free article.
931 results