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Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.
Thompson HL, Smithey MJ, Uhrlaub JL, Jeftić I, Jergović M, White SE, Currier N, Lang AM, Okoye A, Park B, Picker LJ, Surh CD, Nikolich-Žugich J. Thompson HL, et al. Among authors: park b. Aging Cell. 2019 Feb;18(1):e12865. doi: 10.1111/acel.12865. Epub 2018 Nov 14. Aging Cell. 2019. PMID: 30430748 Free PMC article.
Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.
Cicin-Sain L, Messaoudi I, Park B, Currier N, Planer S, Fischer M, Tackitt S, Nikolich-Zugich D, Legasse A, Axthelm MK, Picker LJ, Mori M, Nikolich-Zugich J. Cicin-Sain L, et al. Among authors: park b. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19960-5. doi: 10.1073/pnas.0705905104. Epub 2007 Dec 4. Proc Natl Acad Sci U S A. 2007. PMID: 18056811 Free PMC article.
Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates.
Cicin-Sain L, Smyk-Pearson S, Currier N, Byrd L, Koudelka C, Robinson T, Swarbrick G, Tackitt S, Legasse A, Fischer M, Nikolich-Zugich D, Park B, Hobbs T, Doane CJ, Mori M, Axthelm MK, Lewinsohn DA, Nikolich-Zugich J. Cicin-Sain L, et al. Among authors: park b. J Immunol. 2010 Jun 15;184(12):6739-45. doi: 10.4049/jimmunol.0904193. Epub 2010 May 17. J Immunol. 2010. PMID: 20483749 Free PMC article.
Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors.
Metcalf TU, Cubas RA, Ghneim K, Cartwright MJ, Grevenynghe JV, Richner JM, Olagnier DP, Wilkinson PA, Cameron MJ, Park BS, Hiscott JB, Diamond MS, Wertheimer AM, Nikolich-Zugich J, Haddad EK. Metcalf TU, et al. Among authors: park bs. Aging Cell. 2015 Jun;14(3):421-32. doi: 10.1111/acel.12320. Epub 2015 Feb 27. Aging Cell. 2015. PMID: 25728020 Free PMC article.
Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques.
Okoye AA, Rohankhedkar M, Konfe AL, Abana CO, Reyes MD, Clock JA, Duell DM, Sylwester AW, Sammader P, Legasse AW, Park BS, Axthelm MK, Nikolich-Žugich J, Picker LJ. Okoye AA, et al. J Immunol. 2015 Nov 1;195(9):4292-305. doi: 10.4049/jimmunol.1500609. Epub 2015 Sep 28. J Immunol. 2015. PMID: 26416281 Free PMC article.
Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques.
DeGottardi MQ, Okoye AA, Vaidya M, Talla A, Konfe AL, Reyes MD, Clock JA, Duell DM, Legasse AW, Sabnis A, Park BS, Axthelm MK, Estes JD, Reiman KA, Sekaly RP, Picker LJ. DeGottardi MQ, et al. J Immunol. 2016 Aug 15;197(4):1183-98. doi: 10.4049/jimmunol.1600065. Epub 2016 Jul 18. J Immunol. 2016. PMID: 27430715 Free PMC article.
Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques.
Burwitz BJ, Malouli D, Bimber BN, Reed JS, Ventura AB, Hancock MH, Uebelhoer LS, Bhusari A, Hammond KB, Espinosa Trethewy RG, Klug A, Legasse AW, Axthelm MK, Nelson JA, Park BS, Streblow DN, Hansen SG, Picker LJ, Früh K, Sacha JB. Burwitz BJ, et al. Among authors: park bs. PLoS Pathog. 2016 Nov 9;12(11):e1006014. doi: 10.1371/journal.ppat.1006014. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27829026 Free PMC article.
9,210 results