Smithey MJ - Search Results

1

Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.

Thompson HL, Smithey MJ, Uhrlaub JL, Jeftić I, Jergović M, White SE, Currier N, Lang AM, Okoye A, Park B, Picker LJ, Surh CD, Nikolich-Žugich J. Thompson HL, et al. Among authors: smithey mj. Aging Cell. 2019 Feb;18(1):e12865. doi: 10.1111/acel.12865. Epub 2018 Nov 14. Aging Cell. 2019. PMID: 30430748 Free PMC article.

2

Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.

Rudd BD, Venturi V, Smithey MJ, Way SS, Davenport MP, Nikolich-Zugich J. Rudd BD, et al. Among authors: smithey mj. J Immunol. 2010 Mar 15;184(6):2958-2965. doi: 10.4049/jimmunol.0903493. Epub 2010 Feb 17. J Immunol. 2010. PMID: 20164421 Free PMC article.

3

Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice.

Smithey MJ, Renkema KR, Rudd BD, Nikolich-Žugich J. Smithey MJ, et al. Eur J Immunol. 2011 May;41(5):1352-64. doi: 10.1002/eji.201041141. Epub 2011 Apr 14. Eur J Immunol. 2011. PMID: 21469120 Free PMC article.

4

Age-related changes in CD8 T cell homeostasis and immunity to infection.

Nikolich-Žugich J, Li G, Uhrlaub JL, Renkema KR, Smithey MJ. Nikolich-Žugich J, et al. Among authors: smithey mj. Semin Immunol. 2012 Oct;24(5):356-64. doi: 10.1016/j.smim.2012.04.009. Epub 2012 May 1. Semin Immunol. 2012. PMID: 22554418 Free PMC article. Review.

5

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium.

Li G, Smithey MJ, Rudd BD, Nikolich-Žugich J. Li G, et al. Among authors: smithey mj. Aging Cell. 2012 Dec;11(6):968-77. doi: 10.1111/j.1474-9726.2012.00867.x. Epub 2012 Aug 30. Aging Cell. 2012. PMID: 22862959 Free PMC article.

6

Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life.

Smithey MJ, Li G, Venturi V, Davenport MP, Nikolich-Žugich J. Smithey MJ, et al. J Immunol. 2012 Dec 1;189(11):5356-66. doi: 10.4049/jimmunol.1201867. Epub 2012 Oct 19. J Immunol. 2012. PMID: 23087407 Free PMC article.

7

Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging.

Renkema KR, Li G, Wu A, Smithey MJ, Nikolich-Žugich J. Renkema KR, et al. Among authors: smithey mj. J Immunol. 2014 Jan 1;192(1):151-9. doi: 10.4049/jimmunol.1301453. Epub 2013 Nov 29. J Immunol. 2014. PMID: 24293630 Free PMC article.

8

Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections.

Goldberg EL, Smithey MJ, Lutes LK, Uhrlaub JL, Nikolich-Žugich J. Goldberg EL, et al. Among authors: smithey mj. J Immunol. 2014 Jul 15;193(2):757-63. doi: 10.4049/jimmunol.1400188. Epub 2014 Jun 9. J Immunol. 2014. PMID: 24913978 Free PMC article.

9

Histone deacetylation critically determines T cell subset radiosensitivity.

Pugh JL, Sukhina AS, Seed TM, Manley NR, Sempowski GD, van den Brink MR, Smithey MJ, Nikolich-Žugich J. Pugh JL, et al. Among authors: smithey mj. J Immunol. 2014 Aug 1;193(3):1451-8. doi: 10.4049/jimmunol.1400434. Epub 2014 Jul 2. J Immunol. 2014. PMID: 24990082 Free PMC article.

10

Lost in translation: mice, men and cutaneous immunity in old age.

Smithey MJ, Uhrlaub JL, Li G, Vukmanovic-Stejic M, Akbar AN, Nikolich-Zugich J. Smithey MJ, et al. Biogerontology. 2015 Apr;16(2):203-8. doi: 10.1007/s10522-014-9517-0. Epub 2014 Jul 16. Biogerontology. 2015. PMID: 25027761 Review.

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