Tomasicchio M - Search Results

1

The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis-Specific Host Immunity Through the Glucocorticoid Receptor.

Tomasicchio M, Davids M, Pooran A, Theron G, Smith L, Semple L, Meldau R, Hapgood JP, Dheda K. Tomasicchio M, et al. J Infect Dis. 2019 Apr 8;219(8):1329-1337. doi: 10.1093/infdis/jiy657. J Infect Dis. 2019. PMID: 30452655 Free PMC article.

2

Modulation of HIV-1 virulence via the host glucocorticoid receptor: towards further understanding the molecular mechanisms of HIV-1 pathogenesis.

Hapgood JP, Tomasicchio M. Hapgood JP, et al. Among authors: tomasicchio m. Arch Virol. 2010 Jul;155(7):1009-19. doi: 10.1007/s00705-010-0678-0. Epub 2010 May 6. Arch Virol. 2010. PMID: 20446002 Review.

3

The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor.

Tomasicchio M, Avenant C, Du Toit A, Ray RM, Hapgood JP. Tomasicchio M, et al. PLoS One. 2013 May 3;8(5):e62895. doi: 10.1371/journal.pone.0062895. Print 2013. PLoS One. 2013. PMID: 23658782 Free PMC article.

4

Differential glucocorticoid receptor-mediated effects on immunomodulatory gene expression by progestin contraceptives: implications for HIV-1 pathogenesis.

Hapgood JP, Ray RM, Govender Y, Avenant C, Tomasicchio M. Hapgood JP, et al. Among authors: tomasicchio m. Am J Reprod Immunol. 2014 Jun;71(6):505-12. doi: 10.1111/aji.12214. Epub 2014 Feb 18. Am J Reprod Immunol. 2014. PMID: 24547700 Review.

5

The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates.

Tomasicchio M, Theron G, Pietersen E, Streicher E, Stanley-Josephs D, van Helden P, Warren R, Dheda K. Tomasicchio M, et al. Sci Rep. 2016 Feb 10;6:17850. doi: 10.1038/srep17850. Sci Rep. 2016. PMID: 26860462 Free PMC article.

6

Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial.

Calligaro GL, Zijenah LS, Peter JG, Theron G, Buser V, McNerney R, Bara W, Bandason T, Govender U, Tomasicchio M, Smith L, Mayosi BM, Dheda K. Calligaro GL, et al. Among authors: tomasicchio m. Lancet Infect Dis. 2017 Apr;17(4):441-450. doi: 10.1016/S1473-3099(16)30384-X. Epub 2017 Jan 5. Lancet Infect Dis. 2017. PMID: 28063795 Clinical Trial.

7

Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels.

Maritz MF, Ray RM, Bick AJ, Tomasicchio M, Woodland JG, Govender Y, Avenant C, Hapgood JP. Maritz MF, et al. Among authors: tomasicchio m. PLoS One. 2018 Apr 26;13(4):e0196043. doi: 10.1371/journal.pone.0196043. eCollection 2018. PLoS One. 2018. PMID: 29698514 Free PMC article.

8

An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells.

Tomasicchio M, Semple L, Esmail A, Meldau R, Randall P, Pooran A, Davids M, Cairncross L, Anderson D, Downs J, Malherbe F, Novitzky N, Panieri E, Oelofse S, Londt R, Naiker T, Dheda K. Tomasicchio M, et al. Cancer Immunol Immunother. 2019 Jan;68(1):71-83. doi: 10.1007/s00262-018-2238-5. Epub 2018 Oct 3. Cancer Immunol Immunother. 2019. PMID: 30283982 Free PMC article.

9

The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations.

Ray RM, Maritz MF, Avenant C, Tomasicchio M, Dlamini S, van der Spuy Z, Hapgood JP. Ray RM, et al. Among authors: tomasicchio m. Sci Rep. 2019 Mar 13;9(1):4334. doi: 10.1038/s41598-019-40756-7. Sci Rep. 2019. PMID: 30867477 Free PMC article.

10

A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin.

Davids M, Pooran A, Hermann C, Mottay L, Thompson F, Cardenas J, Gu J, Koeuth T, Meldau R, Limberis J, Gina P, Srivastava S, Calder B, Esmail A, Tomasicchio M, Blackburn J, Gumbo T, Dheda K. Davids M, et al. Among authors: tomasicchio m. Am J Respir Crit Care Med. 2020 May 15;201(10):1277-1291. doi: 10.1164/rccm.201908-1580OC. Am J Respir Crit Care Med. 2020. PMID: 31860339

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