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Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Kinnebrew M, Woolley RE, Ansell TB, Byrne EFX, Frigui S, Luchetti G, Sircar R, Nachtergaele S, Mydock-McGrane L, Krishnan K, Newstead S, Sansom MSP, Covey DF, Siebold C, Rohatgi R. Kinnebrew M, et al. Among authors: woolley re. Sci Adv. 2022 Jun 3;8(22):eabm5563. doi: 10.1126/sciadv.abm5563. Epub 2022 Jun 3. Sci Adv. 2022. PMID: 35658032 Free PMC article.
Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift.
Knight MJ, Woolley RE, Kwok A, Parsons S, Jones HBL, Gulácsy CE, Phaal P, Kassaar O, Dawkins K, Rodriguez E, Marques A, Bowsher L, Wells SA, Watts A, van den Elsen JMH, Turner A, O'Hara J, Pudney CR. Knight MJ, et al. Among authors: woolley re. Biochem J. 2020 Sep 30;477(18):3599-3612. doi: 10.1042/BCJ20200580. Biochem J. 2020. PMID: 32869839 Free PMC article.
Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Gherardin NA, Keller AN, Woolley RE, Le Nours J, Ritchie DS, Neeson PJ, Birkinshaw RW, Eckle SBG, Waddington JN, Liu L, Fairlie DP, Uldrich AP, Pellicci DG, McCluskey J, Godfrey DI, Rossjohn J. Gherardin NA, et al. Among authors: woolley re. Immunity. 2016 Jan 19;44(1):32-45. doi: 10.1016/j.immuni.2015.12.005. Epub 2016 Jan 12. Immunity. 2016. PMID: 26795251 Free article.