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Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.
Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS. Morioka S, et al. Among authors: makowski l. Nature. 2018 Nov;563(7733):714-718. doi: 10.1038/s41586-018-0735-5. Epub 2018 Nov 21. Nature. 2018. PMID: 30464343 Free PMC article.
Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma.
Bhatt AP, Jacobs SR, Freemerman AJ, Makowski L, Rathmell JC, Dittmer DP, Damania B. Bhatt AP, et al. Among authors: makowski l. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11818-23. doi: 10.1073/pnas.1205995109. Epub 2012 Jun 29. Proc Natl Acad Sci U S A. 2012. PMID: 22752304 Free PMC article.
Lack of myeloid Fatp1 increases atherosclerotic lesion size in Ldlr-/- mice.
Zhao L, Cozzo AJ, Johnson AR, Christensen T, Freemerman AJ, Bear JE, Rotty JD, Bennett BJ, Makowski L. Zhao L, et al. Among authors: makowski l. Atherosclerosis. 2017 Nov;266:182-189. doi: 10.1016/j.atherosclerosis.2017.10.009. Epub 2017 Oct 7. Atherosclerosis. 2017. PMID: 29035781 Free PMC article.
Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1.
Freemerman AJ, Zhao L, Pingili AK, Teng B, Cozzo AJ, Fuller AM, Johnson AR, Milner JJ, Lim MF, Galanko JA, Beck MA, Bear JE, Rotty JD, Bezavada L, Smallwood HS, Puchowicz MA, Liu J, Locasale JW, Lee DP, Bennett BJ, Abel ED, Rathmell JC, Makowski L. Freemerman AJ, et al. Among authors: makowski l. J Immunol. 2019 Feb 15;202(4):1265-1286. doi: 10.4049/jimmunol.1800002. Epub 2019 Jan 18. J Immunol. 2019. PMID: 30659108 Free PMC article.
Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer.
Chaib M, Holt JR, Fisher EL, Sipe LM, Bohm MS, Joseph SC, Simmons BW, Eugin Simon S, Yarbro JR, Tanveer U, Halle JL, Carson JA, Hollingsworth TJ, Wei Q, Rathmell JC, Thomas PG, Hayes DN, Makowski L. Chaib M, et al. Among authors: makowski l. Sci Adv. 2023 Dec 22;9(51):eadd3231. doi: 10.1126/sciadv.add3231. Epub 2023 Dec 22. Sci Adv. 2023. PMID: 38134280 Free PMC article.
Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation.
Johnson AR, Qin Y, Cozzo AJ, Freemerman AJ, Huang MJ, Zhao L, Sampey BP, Milner JJ, Beck MA, Damania B, Rashid N, Galanko JA, Lee DP, Edin ML, Zeldin DC, Fueger PT, Dietz B, Stahl A, Wu Y, Mohlke KL, Makowski L. Johnson AR, et al. Among authors: makowski l. Mol Metab. 2016 Apr 23;5(7):506-526. doi: 10.1016/j.molmet.2016.04.005. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408776 Free PMC article.
Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.
Porrello A, Leslie PL, Harrison EB, Gorentla BK, Kattula S, Ghosh SK, Azam SH, Holtzhausen A, Chao YL, Hayward MC, Waugh TA, Bae S, Godfrey V, Randell SH, Oderup C, Makowski L, Weiss J, Wilkerson MD, Hayes DN, Earp HS, Baldwin AS, Wolberg AS, Pecot CV. Porrello A, et al. Among authors: makowski l. Nat Commun. 2018 May 18;9(1):1988. doi: 10.1038/s41467-018-04355-w. Nat Commun. 2018. PMID: 29777108 Free PMC article.
Gene-by-environment modulation of lifespan and weight gain in the murine BXD family.
Roy S, Sleiman MB, Jha P, Ingels JF, Chapman CJ, McCarty MS, Ziebarth JD, Hook M, Sun A, Zhao W, Huang J, Neuner SM, Wilmott LA, Shapaker TM, Centeno AG, Ashbrook DG, Mulligan MK, Kaczorowski CC, Makowski L, Cui Y, Read RW, Miller RA, Mozhui K, Williams EG, Sen S, Lu L, Auwerx J, Williams RW. Roy S, et al. Among authors: makowski l. Nat Metab. 2021 Sep;3(9):1217-1227. doi: 10.1038/s42255-021-00449-w. Epub 2021 Sep 22. Nat Metab. 2021. PMID: 34552269 Free PMC article.
244 results