Long-term hepatitis B infection in a scalable hepatic co-culture system.
Winer BY, Huang TS, Pludwinski E, Heller B, Wojcik F, Lipkowitz GE, Parekh A, Cho C, Shrirao A, Muir TW, Novik E, Ploss A.
Winer BY, et al.
Nat Commun. 2017 Jul 25;8(1):125. doi: 10.1038/s41467-017-00200-8.
Nat Commun. 2017.
PMID: 28743900
Free PMC article.
The study of hepatitis B virus and development of curative antivirals are hampered by a scarcity of models that mimic infection in a physiologically relevant, cellular context. ...The platform is scalable to microwell formats, and we provide proof-of-concept for its use in …
The study of hepatitis B virus and development of curative antivirals are hampered by a scarcity of models that mimic infection in a …