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Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8-GP) and development of a human pharmacokinetic prediction model.
Rode F, Almholt K, Petersen M, Kreilgaard M, Kjalke M, Karpf DM, Groth AV, Johansen PB, Larsen LF, Loftager M, Haaning J. Rode F, et al. Among authors: johansen pb. J Thromb Haemost. 2018 Jun;16(6):1141-1152. doi: 10.1111/jth.14013. Epub 2018 May 10. J Thromb Haemost. 2018. PMID: 29582559 Free article.
A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.
Stennicke HR, Kjalke M, Karpf DM, Balling KW, Johansen PB, Elm T, Øvlisen K, Möller F, Holmberg HL, Gudme CN, Persson E, Hilden I, Pelzer H, Rahbek-Nielsen H, Jespersgaard C, Bogsnes A, Pedersen AA, Kristensen AK, Peschke B, Kappers W, Rode F, Thim L, Tranholm M, Ezban M, Olsen EH, Bjørn SE. Stennicke HR, et al. Among authors: johansen pb. Blood. 2013 Mar 14;121(11):2108-16. doi: 10.1182/blood-2012-01-407494. Epub 2013 Jan 18. Blood. 2013. PMID: 23335368 Free PMC article.
Automated registration of tail bleeding in rats.
Johansen PB, Henriksen L, Andresen PR, Lauritzen B, Jensen KL, Juhl TN, Tranholm M. Johansen PB, et al. Thromb Haemost. 2008 May;99(5):956-62. doi: 10.1160/TH07-12-0738. Thromb Haemost. 2008. PMID: 18449428
119 results