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Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis.
Choi Y, Park SJ, Sun Y, Yoo JS, Pudupakam RS, Foo SS, Shin WJ, Chen SB, Tsichlis PN, Lee WJ, Lee JS, Li W, Brennan B, Choi YK, Jung JU. Choi Y, et al. Among authors: tsichlis pn. Nat Microbiol. 2019 Mar;4(3):429-437. doi: 10.1038/s41564-018-0329-x. Epub 2019 Jan 7. Nat Microbiol. 2019. PMID: 30617349 Free PMC article.
Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation.
Serebrennikova OB, Tsatsanis C, Mao C, Gounaris E, Ren W, Siracusa LD, Eliopoulos AG, Khazaie K, Tsichlis PN. Serebrennikova OB, et al. Among authors: tsichlis pn. Proc Natl Acad Sci U S A. 2012 May 1;109(18):E1082-91. doi: 10.1073/pnas.1115098109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451924 Free PMC article.
Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.
Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, Jankovic D, Tsichlis PN, O'Shea JJ. Watford WT, et al. Among authors: tsichlis pn. J Exp Med. 2008 Nov 24;205(12):2803-12. doi: 10.1084/jem.20081461. Epub 2008 Nov 10. J Exp Med. 2008. PMID: 19001140 Free PMC article.
223 results