Shen R - Search Results

1

Tumor mutational load predicts survival after immunotherapy across multiple cancer types.

Samstein RM, Lee CH, Shoushtari AN, Hellmann MD, Shen R, Janjigian YY, Barron DA, Zehir A, Jordan EJ, Omuro A, Kaley TJ, Kendall SM, Motzer RJ, Hakimi AA, Voss MH, Russo P, Rosenberg J, Iyer G, Bochner BH, Bajorin DF, Al-Ahmadie HA, Chaft JE, Rudin CM, Riely GJ, Baxi S, Ho AL, Wong RJ, Pfister DG, Wolchok JD, Barker CA, Gutin PH, Brennan CW, Tabar V, Mellinghoff IK, DeAngelis LM, Ariyan CE, Lee N, Tap WD, Gounder MM, D'Angelo SP, Saltz L, Stadler ZK, Scher HI, Baselga J, Razavi P, Klebanoff CA, Yaeger R, Segal NH, Ku GY, DeMatteo RP, Ladanyi M, Rizvi NA, Berger MF, Riaz N, Solit DB, Chan TA, Morris LGT. Samstein RM, et al. Among authors: shen r. Nat Genet. 2019 Feb;51(2):202-206. doi: 10.1038/s41588-018-0312-8. Epub 2019 Jan 14. Nat Genet. 2019. PMID: 30643254 Free PMC article.

2

Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis.

Shen R, Olshen AB, Ladanyi M. Shen R, et al. Bioinformatics. 2009 Nov 15;25(22):2906-12. doi: 10.1093/bioinformatics/btp543. Epub 2009 Sep 16. Bioinformatics. 2009. PMID: 19759197 Free PMC article.

3

Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.

Regales L, Gong Y, Shen R, de Stanchina E, Vivanco I, Goel A, Koutcher JA, Spassova M, Ouerfelli O, Mellinghoff IK, Zakowski MF, Politi KA, Pao W. Regales L, et al. Among authors: shen r. J Clin Invest. 2009 Oct;119(10):3000-10. doi: 10.1172/JCI38746. Epub 2009 Sep 14. J Clin Invest. 2009. PMID: 19759520 Free PMC article.

4

High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507).

Gong Y, Yao E, Shen R, Goel A, Arcila M, Teruya-Feldstein J, Zakowski MF, Frankel S, Peifer M, Thomas RK, Ladanyi M, Pao W. Gong Y, et al. Among authors: shen r. PLoS One. 2009 Oct 6;4(10):e7273. doi: 10.1371/journal.pone.0007273. PLoS One. 2009. PMID: 19806209 Free PMC article.

5

Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas.

Girard N, Shen R, Guo T, Zakowski MF, Heguy A, Riely GJ, Huang J, Lau C, Lash AE, Ladanyi M, Viale A, Antonescu CR, Travis WD, Rusch VW, Kris MG, Pao W. Girard N, et al. Among authors: shen r. Clin Cancer Res. 2009 Nov 15;15(22):6790-9. doi: 10.1158/1078-0432.CCR-09-0644. Epub 2009 Oct 27. Clin Cancer Res. 2009. PMID: 19861435 Free PMC article.

6

Pack-years of cigarette smoking as a prognostic factor in patients with stage IIIB/IV nonsmall cell lung cancer.

Janjigian YY, McDonnell K, Kris MG, Shen R, Sima CS, Bach PB, Rizvi NA, Riely GJ. Janjigian YY, et al. Among authors: shen r. Cancer. 2010 Feb 1;116(3):670-5. doi: 10.1002/cncr.24813. Cancer. 2010. PMID: 20029977 Free PMC article.

7

A phase 2 study of pemetrexed plus gemcitabine every 2 weeks for patients with recurrent or metastatic head and neck squamous cell cancer.

Fury MG, Haque S, Stambuk H, Shen R, Carlson D, Pfister D. Fury MG, et al. Among authors: shen r. Cancer. 2011 Feb 15;117(4):795-801. doi: 10.1002/cncr.25464. Epub 2010 Oct 4. Cancer. 2011. PMID: 20922785 Free article. Clinical Trial.

8

Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations.

Janjigian YY, Park BJ, Zakowski MF, Ladanyi M, Pao W, D'Angelo SP, Kris MG, Shen R, Zheng J, Azzoli CG. Janjigian YY, et al. Among authors: shen r. J Thorac Oncol. 2011 Mar;6(3):569-75. doi: 10.1097/JTO.0b013e318202bffe. J Thorac Oncol. 2011. PMID: 21150674 Free PMC article.

9

Phase II study of saracatinib (AZD0530) for patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

Fury MG, Baxi S, Shen R, Kelly KW, Lipson BL, Carlson D, Stambuk H, Haque S, Pfister DG. Fury MG, et al. Among authors: shen r. Anticancer Res. 2011 Jan;31(1):249-53. Anticancer Res. 2011. PMID: 21273606 Free PMC article. Clinical Trial.

10

Breast cancer methylomes establish an epigenomic foundation for metastasis.

Fang F, Turcan S, Rimner A, Kaufman A, Giri D, Morris LG, Shen R, Seshan V, Mo Q, Heguy A, Baylin SB, Ahuja N, Viale A, Massague J, Norton L, Vahdat LT, Moynahan ME, Chan TA. Fang F, et al. Among authors: shen r. Sci Transl Med. 2011 Mar 23;3(75):75ra25. doi: 10.1126/scitranslmed.3001875. Sci Transl Med. 2011. PMID: 21430268 Free PMC article.

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