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Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane.
Wang Z, Gurule EE, Brennan TP, Gerold JM, Kwon KJ, Hosmane NN, Kumar MR, Beg SA, Capoferri AA, Ray SC, Ho YC, Hill AL, Siliciano JD, Siliciano RF. Wang Z, et al. Among authors: ho yc. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2575-E2584. doi: 10.1073/pnas.1720665115. Epub 2018 Feb 26. Proc Natl Acad Sci U S A. 2018. PMID: 29483265 Free PMC article.
Single-cell transcriptional landscapes reveal HIV-1-driven aberrant host gene transcription as a potential therapeutic target.
Liu R, Yeh YJ, Varabyou A, Collora JA, Sherrill-Mix S, Talbot CC Jr, Mehta S, Albrecht K, Hao H, Zhang H, Pollack RA, Beg SA, Calvi RM, Hu J, Durand CM, Ambinder RF, Hoh R, Deeks SG, Chiarella J, Spudich S, Douek DC, Bushman FD, Pertea M, Ho YC. Liu R, et al. Among authors: ho yc. Sci Transl Med. 2020 May 13;12(543):eaaz0802. doi: 10.1126/scitranslmed.aaz0802. Sci Transl Med. 2020. PMID: 32404504 Free PMC article.
Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.
Sun Y, Abriola L, Niederer RO, Pedersen SF, Alfajaro MM, Silva Monteiro V, Wilen CB, Ho YC, Gilbert WV, Surovtseva YV, Lindenbach BD, Guo JU. Sun Y, et al. Among authors: ho yc. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2023051118. doi: 10.1073/pnas.2023051118. Proc Natl Acad Sci U S A. 2021. PMID: 34185680 Free PMC article.
TCR-mimic bispecific antibodies to target the HIV-1 reservoir.
Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, Jenike K, Ho YC, Gabelli SB, Kinzler KW, Vogelstein B, Zhou S, Siliciano JD, Sadegh-Nasseri S, Reinherz EL, Siliciano RF. Sengupta S, et al. Among authors: ho yc. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2123406119. doi: 10.1073/pnas.2123406119. Epub 2022 Apr 8. Proc Natl Acad Sci U S A. 2022. PMID: 35394875 Free PMC article.
445 results