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A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.
Somers K, Wen VW, Middlemiss SMC, Osborne B, Forgham H, Jung M, Karsa M, Clifton M, Bongers A, Gao J, Mayoh C, Raoufi-Rad N, Kusnadi EP, Hannan KM, Scott DA, Kwek A, Liu B, Flemming C, Chudakova DA, Pandher R, Failes TW, Lim J, Angeli A, Osterman AL, Imamura T, Kees UR, Supuran CT, Pearson RB, Hannan RD, Davis TP, McCarroll J, Kavallaris M, Turner N, Gudkov AV, Haber M, Norris MD, Henderson MJ. Somers K, et al. Among authors: osterman al. Oncogene. 2019 May;38(20):3824-3842. doi: 10.1038/s41388-018-0666-5. Epub 2019 Jan 22. Oncogene. 2019. PMID: 30670779 Free PMC article.
Structural basis of TLR5-flagellin recognition and signaling.
Yoon SI, Kurnasov O, Natarajan V, Hong M, Gudkov AV, Osterman AL, Wilson IA. Yoon SI, et al. Among authors: osterman al. Science. 2012 Feb 17;335(6070):859-64. doi: 10.1126/science.1215584. Science. 2012. PMID: 22344444 Free PMC article.
Functional specialization in proline biosynthesis of melanoma.
De Ingeniis J, Ratnikov B, Richardson AD, Scott DA, Aza-Blanc P, De SK, Kazanov M, Pellecchia M, Ronai Z, Osterman AL, Smith JW. De Ingeniis J, et al. Among authors: osterman al. PLoS One. 2012;7(9):e45190. doi: 10.1371/journal.pone.0045190. Epub 2012 Sep 14. PLoS One. 2012. PMID: 23024808 Free PMC article.
275 results