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Biosynthesis and Ether-Bridge Formation in Nargenicin Macrolides.
Pidot SJ, Herisse M, Sharkey L, Atkin L, Porter JL, Seemann T, Howden BP, Rizzacasa MA, Stinear TP. Pidot SJ, et al. Among authors: sharkey l. Angew Chem Int Ed Engl. 2019 Mar 18;58(12):3996-4001. doi: 10.1002/anie.201900290. Epub 2019 Feb 11. Angew Chem Int Ed Engl. 2019. PMID: 30677204
Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus.
Monk IR, Shaikh N, Begg SL, Gajdiss M, Sharkey LKR, Lee JYH, Pidot SJ, Seemann T, Kuiper M, Winnen B, Hvorup R, Collins BM, Bierbaum G, Udagedara SR, Morey JR, Pulyani N, Howden BP, Maher MJ, McDevitt CA, King GF, Stinear TP. Monk IR, et al. Among authors: sharkey lkr. Nat Commun. 2019 Jul 11;10(1):3067. doi: 10.1038/s41467-019-10932-4. Nat Commun. 2019. PMID: 31296851 Free PMC article.
Accessible Platform for High-Throughput COVID-19 Molecular Diagnostics and Genome Sequencing Using a Repurposed 3D Printer for RNA Extraction.
Vandelannoote K, Buultjens AH, Li L, Sharkey LK, Herisse M, Pidot SJ, Hoang T, Howden BP, Monk IR, Seemann T, Lee JYH, Stinear TP. Vandelannoote K, et al. Among authors: sharkey lk. ACS Biomater Sci Eng. 2021 Sep 13;7(9):4669-4676. doi: 10.1021/acsbiomaterials.1c00775. Epub 2021 Aug 26. ACS Biomater Sci Eng. 2021. PMID: 34437802 Free article.
Staphylococcus aureus host interactions and adaptation.
Howden BP, Giulieri SG, Wong Fok Lung T, Baines SL, Sharkey LK, Lee JYH, Hachani A, Monk IR, Stinear TP. Howden BP, et al. Among authors: sharkey lk. Nat Rev Microbiol. 2023 Jun;21(6):380-395. doi: 10.1038/s41579-023-00852-y. Epub 2023 Jan 27. Nat Rev Microbiol. 2023. PMID: 36707725 Free PMC article. Review.
The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in Staphylococcus aureus.
Sharkey LKR, Guerillot R, Walsh CJ, Turner AM, Lee JYH, Neville SL, Klatt S, Baines SL, Pidot SJ, Rossello FJ, Seemann T, McWilliam HEG, Cho E, Carter GP, Howden BP, McDevitt CA, Hachani A, Stinear TP, Monk IR. Sharkey LKR, et al. mBio. 2023 Oct 16;14(6):e0226223. doi: 10.1128/mbio.02262-23. Online ahead of print. mBio. 2023. PMID: 37850732 Free PMC article.
Hepatic insufficiency in two juvenile dogs with histoplasmosis.
Whitman RE, Cagle LA, Bosch S, Alas OB, Vilaplana Grosso FR, Lanier CJ, Heinrich DA, Sharkey LC. Whitman RE, et al. Among authors: sharkey lc. Vet Clin Pathol. 2024 Apr 29. doi: 10.1111/vcp.13354. Online ahead of print. Vet Clin Pathol. 2024. PMID: 38684471
192 results