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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity.
Martínez-López M, Iborra S, Conde-Garrosa R, Mastrangelo A, Danne C, Mann ER, Reid DM, Gaboriau-Routhiau V, Chaparro M, Lorenzo MP, Minnerup L, Saz-Leal P, Slack E, Kemp B, Gisbert JP, Dzionek A, Robinson MJ, Rupérez FJ, Cerf-Bensussan N, Brown GD, Bernardo D, LeibundGut-Landmann S, Sancho D. Martínez-López M, et al. Among authors: bernardo d. Immunity. 2019 Feb 19;50(2):446-461.e9. doi: 10.1016/j.immuni.2018.12.020. Epub 2019 Jan 29. Immunity. 2019. PMID: 30709742 Free PMC article.
IL-6 promotes immune responses in human ulcerative colitis and induces a skin-homing phenotype in the dendritic cells and Tcells they stimulate.
Bernardo D, Vallejo-Díez S, Mann ER, Al-Hassi HO, Martínez-Abad B, Montalvillo E, Tee CT, Murugananthan AU, Núñez H, Peake ST, Hart AL, Fernández-Salazar L, Garrote JA, Arranz E, Knight SC. Bernardo D, et al. Eur J Immunol. 2012 May;42(5):1337-53. doi: 10.1002/eji.201142327. Eur J Immunol. 2012. PMID: 22539302 Free article.
Innate immune factors in the development and maintenance of pouchitis.
Landy J, Al-Hassi HO, Ronde E, English NR, Mann ER, Bernardo D, Ciclitira PJ, Clark SK, Knight SC, Hart AL. Landy J, et al. Among authors: bernardo d. Inflamm Bowel Dis. 2014 Nov;20(11):1942-9. doi: 10.1097/MIB.0000000000000182. Inflamm Bowel Dis. 2014. PMID: 25222658
Human gut dendritic cells drive aberrant gut-specific t-cell responses in ulcerative colitis, characterized by increased IL-4 production and loss of IL-22 and IFNγ.
Mann ER, Bernardo D, Ng SC, Rigby RJ, Al-Hassi HO, Landy J, Peake ST, Spranger H, English NR, Thomas LV, Stagg AJ, Knight SC, Hart AL. Mann ER, et al. Among authors: bernardo d. Inflamm Bowel Dis. 2014 Dec;20(12):2299-307. doi: 10.1097/MIB.0000000000000223. Inflamm Bowel Dis. 2014. PMID: 25397892
314 results