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Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development.
Yin Y, Wang Y, Dang W, Xu L, Su J, Zhou X, Wang W, Felczak K, van der Laan LJ, Pankiewicz KW, van der Eijk AA, Bijvelds M, Sprengers D, de Jonge H, Koopmans MP, Metselaar HJ, Peppelenbosch MP, Pan Q. Yin Y, et al. Among authors: felczak k. Antiviral Res. 2016 Sep;133:41-9. doi: 10.1016/j.antiviral.2016.07.017. Epub 2016 Jul 25. Antiviral Res. 2016. PMID: 27468950
Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication.
Wang Y, Wang W, Xu L, Zhou X, Shokrollahi E, Felczak K, van der Laan LJ, Pankiewicz KW, Sprengers D, Raat NJ, Metselaar HJ, Peppelenbosch MP, Pan Q. Wang Y, et al. Among authors: felczak k. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2834-48. doi: 10.1128/AAC.02700-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26926637 Free PMC article.
Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication.
Dang W, Yin Y, Wang Y, Wang W, Su J, Sprengers D, van der Laan LJW, Felczak K, Pankiewicz KW, Chang KO, Koopmans MPG, Metselaar HJ, Peppelenbosch MP, Pan Q. Dang W, et al. Among authors: felczak k. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e01095-17. doi: 10.1128/AAC.01095-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28807916 Free PMC article.
NAD-based inhibitors with anticancer potential.
Felczak K, Vince R, Pankiewicz KW. Felczak K, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):332-6. doi: 10.1016/j.bmcl.2013.11.005. Epub 2013 Nov 14. Bioorg Med Chem Lett. 2014. PMID: 24269162
Nicotinamide Adenine Dinucleotide Based Therapeutics, Update.
Pankiewicz KW, Petrelli R, Singh R, Felczak K. Pankiewicz KW, et al. Among authors: felczak k. Curr Med Chem. 2015;22(34):3991-4028. doi: 10.2174/0929867322666150821100720. Curr Med Chem. 2015. PMID: 26295463 Review.
40 results