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Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture.
Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W, Van Dyck C, D'Hondt M, Ramon A, Vermeulen W, De Winter B, Van Marck E, Van Marck V, Pelckmans P, Michielsen P. Francque S, et al. Lab Invest. 2012 Oct;92(10):1428-39. doi: 10.1038/labinvest.2012.103. Epub 2012 Aug 13. Lab Invest. 2012. PMID: 22890552 Free article.
Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice.
Kwanten WJ, Vandewynckel YP, Martinet W, De Winter BY, Michielsen PP, Van Hoof VO, Driessen A, Timmermans JP, Bedossa P, Van Vlierberghe H, Francque SM. Kwanten WJ, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1;311(4):G599-G609. doi: 10.1152/ajpgi.00418.2015. Epub 2016 Aug 11. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27514483 Free PMC article.
Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin.
Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, Vonghia L, Kwanten WJ, Michielsen P, Vanwolleghem T, Eeckhoute J, Verrijken A, Van Gaal L, Francque S, Staels B. Lefebvre P, et al. Among authors: kwanten wj. JCI Insight. 2017 Jul 6;2(13):e92264. doi: 10.1172/jci.insight.92264. eCollection 2017 Jul 6. JCI Insight. 2017. PMID: 28679947 Free PMC article.
Severe steatosis induces portal hypertension by systemic arterial hyporeactivity and hepatic vasoconstrictor hyperreactivity in rats.
Van der Graaff D, Kwanten WJ, Couturier FJ, Govaerts JS, Verlinden W, Brosius I, D'Hondt M, Driessen A, De Winter BY, De Man JG, Michielsen PP, Francque SM. Van der Graaff D, et al. Among authors: kwanten wj. Lab Invest. 2018 Oct;98(10):1263-1275. doi: 10.1038/s41374-017-0018-z. Epub 2018 Jan 11. Lab Invest. 2018. PMID: 29326427 Free article.
The Belgian Association for Study of the Liver Guidance Document on the Management of Adult and Paediatric Non-Alcoholic Fatty Liver Disease.
Francque S, Lanthier N, Verbeke L, Reynaert H, Van Steenkiste C, Vonghia L, Kwanten WJ, Weyler J, Trépo E, Cassiman D, Smets F, Komuta M, Driessen A, Dirinck E, Danse E, Op de Beeck B, van Craenenbroeck E, Van Nieuwenhove Y, Hubens G, Geerts A, Moreno C. Francque S, et al. Among authors: kwanten wj. Acta Gastroenterol Belg. 2018 Jan-Mar;81(1):55-81. Acta Gastroenterol Belg. 2018. PMID: 29562379 Free article.
30 results