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Age-Dependent Reduction in Asthmatic Pathology through Reprogramming of Postviral Inflammatory Responses.
Hazan G, Eubanks A, Gierasch C, Atkinson J, Fox C, Hernandez-Leyva A, Rosen AL, Kau AL, Agapov E, Alexander-Brett J, Steinberg D, Kelley D, White M, Byers D, Wu K, Keeler SP, Zhang Y, Koenitzer JR, Eiden E, Anderson N, Holtzman MJ, Haspel J. Hazan G, et al. Among authors: keeler sp. J Immunol. 2022 Mar 15;208(6):1467-1482. doi: 10.4049/jimmunol.2101094. Epub 2022 Feb 16. J Immunol. 2022. PMID: 35173037 Free PMC article.
Basal epithelial stem cells cross an alarmin checkpoint for postviral lung disease.
Wu K, Kamimoto K, Zhang Y, Yang K, Keeler SP, Gerovac BJ, Agapov EV, Austin SP, Yantis J, Gissy KA, Byers DE, Alexander-Brett J, Hoffmann CM, Wallace M, Hughes ME, Crouch EC, Morris SA, Holtzman MJ. Wu K, et al. Among authors: keeler sp. J Clin Invest. 2021 Oct 1;131(19):e149336. doi: 10.1172/JCI149336. J Clin Invest. 2021. PMID: 34343135 Free PMC article.
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.
Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, Holtzman MJ, Diamond MS. Winkler ES, et al. Among authors: keeler sp. Nat Immunol. 2020 Nov;21(11):1327-1335. doi: 10.1038/s41590-020-0778-2. Epub 2020 Aug 24. Nat Immunol. 2020. PMID: 32839612 Free PMC article.
Chloride channel accessory 1 gene deficiency causes selective loss of mucus production in a new pig model.
Keeler SP, Yantis J, Gerovac BJ, Youkilis SL, Podgorny S, Mao D, Zhang Y, Whitworth KM, Redel B, Samuel MS, Wells KD, Prather RS, Holtzman MJ. Keeler SP, et al. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1;322(6):L842-L852. doi: 10.1152/ajplung.00443.2021. Epub 2022 Apr 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35438004 Free PMC article.
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.
Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, Fremont DH, Greco S, McCray PB Jr, Perlman S, Holtzman MJ, Ellebedy AH, Diamond MS. Hassan AO, et al. Among authors: keeler sp. Cell. 2020 Aug 6;182(3):744-753.e4. doi: 10.1016/j.cell.2020.06.011. Epub 2020 Jun 10. Cell. 2020. PMID: 32553273 Free PMC article.
39 results