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C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD.
O'Rourke JG, Bogdanik L, Muhammad AKMG, Gendron TF, Kim KJ, Austin A, Cady J, Liu EY, Zarrow J, Grant S, Ho R, Bell S, Carmona S, Simpkinson M, Lall D, Wu K, Daughrity L, Dickson DW, Harms MB, Petrucelli L, Lee EB, Lutz CM, Baloh RH. O'Rourke JG, et al. Among authors: muhammad akmg. Neuron. 2015 Dec 2;88(5):892-901. doi: 10.1016/j.neuron.2015.10.027. Neuron. 2015. PMID: 26637796 Free PMC article.
C9orf72 in myeloid cells suppresses STING-induced inflammation.
McCauley ME, O'Rourke JG, Yáñez A, Markman JL, Ho R, Wang X, Chen S, Lall D, Jin M, Muhammad AKMG, Bell S, Landeros J, Valencia V, Harms M, Arditi M, Jefferies C, Baloh RH. McCauley ME, et al. Among authors: muhammad akmg. Nature. 2020 Sep;585(7823):96-101. doi: 10.1038/s41586-020-2625-x. Epub 2020 Aug 19. Nature. 2020. PMID: 32814898 Free PMC article.
C9orf72 is required for proper macrophage and microglial function in mice.
O'Rourke JG, Bogdanik L, Yáñez A, Lall D, Wolf AJ, Muhammad AK, Ho R, Carmona S, Vit JP, Zarrow J, Kim KJ, Bell S, Harms MB, Miller TM, Dangler CA, Underhill DM, Goodridge HS, Lutz CM, Baloh RH. O'Rourke JG, et al. Science. 2016 Mar 18;351(6279):1324-9. doi: 10.1126/science.aaf1064. Science. 2016. PMID: 26989253 Free PMC article.
Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion.
Sareen D, O'Rourke JG, Meera P, Muhammad AK, Grant S, Simpkinson M, Bell S, Carmona S, Ornelas L, Sahabian A, Gendron T, Petrucelli L, Baughn M, Ravits J, Harms MB, Rigo F, Bennett CF, Otis TS, Svendsen CN, Baloh RH. Sareen D, et al. Sci Transl Med. 2013 Oct 23;5(208):208ra149. doi: 10.1126/scitranslmed.3007529. Sci Transl Med. 2013. PMID: 24154603 Free PMC article.
Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics.
Candolfi M, Xiong W, Yagiz K, Liu C, Muhammad AK, Puntel M, Foulad D, Zadmehr A, Ahlzadeh GE, Kroeger KM, Tesarfreund M, Lee S, Debinski W, Sareen D, Svendsen CN, Rodriguez R, Lowenstein PR, Castro MG. Candolfi M, et al. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20021-6. doi: 10.1073/pnas.1008261107. Epub 2010 Oct 28. Proc Natl Acad Sci U S A. 2010. PMID: 21030678 Free PMC article.
35 results