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Rational design of a flavivirus vaccine by abolishing viral RNA 2'-O methylation.
Li SH, Dong H, Li XF, Xie X, Zhao H, Deng YQ, Wang XY, Ye Q, Zhu SY, Wang HJ, Zhang B, Leng QB, Zuest R, Qin ED, Qin CF, Shi PY. Li SH, et al. Among authors: shi py. J Virol. 2013 May;87(10):5812-9. doi: 10.1128/JVI.02806-12. Epub 2013 Mar 13. J Virol. 2013. PMID: 23487465 Free PMC article.
Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques.
Züst R, Dong H, Li XF, Chang DC, Zhang B, Balakrishnan T, Toh YX, Jiang T, Li SH, Deng YQ, Ellis BR, Ellis EM, Poidinger M, Zolezzi F, Qin CF, Shi PY, Fink K. Züst R, et al. Among authors: shi py. PLoS Pathog. 2013;9(8):e1003521. doi: 10.1371/journal.ppat.1003521. Epub 2013 Aug 1. PLoS Pathog. 2013. PMID: 23935499 Free PMC article.
A chimeric dengue virus vaccine using Japanese encephalitis virus vaccine strain SA14-14-2 as backbone is immunogenic and protective against either parental virus in mice and nonhuman primates.
Li XF, Deng YQ, Yang HQ, Zhao H, Jiang T, Yu XD, Li SH, Ye Q, Zhu SY, Wang HJ, Zhang Y, Ma J, Yu YX, Liu ZY, Li YH, Qin ED, Shi PY, Qin CF. Li XF, et al. Among authors: shi py. J Virol. 2013 Dec;87(24):13694-705. doi: 10.1128/JVI.00931-13. Epub 2013 Oct 9. J Virol. 2013. PMID: 24109223 Free PMC article.
Flavivirus RNA methylation.
Dong H, Fink K, Züst R, Lim SP, Qin CF, Shi PY. Dong H, et al. Among authors: shi py. J Gen Virol. 2014 Apr;95(Pt 4):763-778. doi: 10.1099/vir.0.062208-0. Epub 2014 Jan 31. J Gen Virol. 2014. PMID: 24486628 Review.
Determinants of Dengue Virus NS4A Protein Oligomerization.
Lee CM, Xie X, Zou J, Li SH, Lee MY, Dong H, Qin CF, Kang C, Shi PY. Lee CM, et al. Among authors: shi py. J Virol. 2015 Jun;89(12):6171-83. doi: 10.1128/JVI.00546-15. Epub 2015 Apr 1. J Virol. 2015. PMID: 25833044 Free PMC article.
474 results