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Glutaminolysis and lipoproteins are key factors in late immune recovery in successfully treated HIV-infected patients.
Rosado-Sánchez I, Rodríguez-Gallego E, Peraire J, Viladés C, Herrero P, Fanjul F, Gutiérrez F, Bernal E, Pelazas R, Leal M, Veloso S, López-Dupla M, Blanco J, Vidal F, Pacheco YM, Rull A. Rosado-Sánchez I, et al. Among authors: leal m. Clin Sci (Lond). 2019 Apr 29;133(8):997-1010. doi: 10.1042/CS20190111. Print 2019 Apr 30. Clin Sci (Lond). 2019. PMID: 30952809
Evaluation of the pharmacogenetics of immune recovery in treated HIV-infected patients.
Peraire J, Viladés C, Pacheco YM, López-Dupla M, Domingo P, Gutiérrez M, Rosado I, Leal M, Richart C, Vidal F. Peraire J, et al. Among authors: leal m. Expert Opin Drug Metab Toxicol. 2014 Jan;10(1):81-101. doi: 10.1517/17425255.2014.854330. Epub 2013 Nov 21. Expert Opin Drug Metab Toxicol. 2014. PMID: 24256435 Review.
A baseline metabolomic signature is associated with immunological CD4+ T-cell recovery after 36 months of antiretroviral therapy in HIV-infected patients.
Rodríguez-Gallego E, Gómez J, Pacheco YM, Peraire J, Viladés C, Beltrán-Debón R, Mallol R, López-Dupla M, Veloso S, Alba V, Blanco J, Cañellas N, Rull A, Leal M, Correig X, Domingo P, Vidal F. Rodríguez-Gallego E, et al. Among authors: leal m. AIDS. 2018 Mar 13;32(5):565-573. doi: 10.1097/QAD.0000000000001730. AIDS. 2018. PMID: 29280761 Free PMC article.
Circulating metabolomic profile can predict dyslipidemia in HIV patients undergoing antiretroviral therapy.
Rodríguez-Gallego E, Gómez J, Domingo P, Ferrando-Martínez S, Peraire J, Viladés C, Veloso S, López-Dupla M, Beltrán-Debón R, Alba V, Vargas M, Castellano AJ, Leal M, Pacheco YM, Ruiz-Mateos E, Gutiérrez F, Vidal F, Rull A; CORIS-NADES events Study Group. Rodríguez-Gallego E, et al. Among authors: leal m. Atherosclerosis. 2018 Jun;273:28-36. doi: 10.1016/j.atherosclerosis.2018.04.008. Epub 2018 Apr 9. Atherosclerosis. 2018. PMID: 29677628 Free article.
Higher levels of IL-6, CD4 turnover and Treg frequency are already present before cART in HIV-infected subjects with later low CD4 recovery.
Rosado-Sánchez I, Jarrín I, Pozo-Balado MM, de Pablo-Bernal RS, Herrero-Fernández I, Alvarez-Ríos AI, Rodríguez-Gallego E, Genebat M, Vera M, Berenguer J, Martín ML, Bernal E, Vidal F, Blanco J, Leal M, Pacheco YM. Rosado-Sánchez I, et al. Among authors: leal m. Antiviral Res. 2017 Jun;142:76-82. doi: 10.1016/j.antiviral.2017.03.015. Epub 2017 Mar 24. Antiviral Res. 2017. PMID: 28343846
Severe immune dysregulation affects CD4⁺CD25(hi)FoxP3⁺ regulatory T cells in HIV-infected patients with low-level CD4 T-cell repopulation despite suppressive highly active antiretroviral therapy.
Méndez-Lagares G, Pozo-Balado MM, Genebat M, García Pergañeda A, Leal M, Pacheco YM. Méndez-Lagares G, et al. Among authors: leal m. J Infect Dis. 2012 May 15;205(10):1501-9. doi: 10.1093/infdis/jis230. Epub 2012 Mar 28. J Infect Dis. 2012. PMID: 22457273
HIV-1/HAART-Related Lipodystrophy Syndrome (HALS) Is Associated with Decreased Circulating sTWEAK Levels.
López-Dupla M, Maymó-Masip E, Martínez E, Domingo P, Leal M, Peraire J, Viladés C, Veloso S, Arnedo M, Ferrando-Martínez S, Beltrán-Debón R, Alba V, Gatell JM, Vendrell J, Vidal F, Chacón MR. López-Dupla M, et al. Among authors: leal m. PLoS One. 2015 Dec 14;10(12):e0144789. doi: 10.1371/journal.pone.0144789. eCollection 2015. PLoS One. 2015. PMID: 26658801 Free PMC article.
1,407 results